Fig. 3: Measurement of inflammation markers in Ect, End, and VK2 cells in response to M. mulieris (MM) exposure with or without hTLR2 and/or hTLR5 inhibitors. | npj Biofilms and Microbiomes

Fig. 3: Measurement of inflammation markers in Ect, End, and VK2 cells in response to M. mulieris (MM) exposure with or without hTLR2 and/or hTLR5 inhibitors.

From: Mobiluncus mulieris alters the transcriptomic profile of cervicovaginal epithelial cells, shedding light on molecular drivers of adverse reproductive outcomes

Fig. 3

a IL-6, b IL-8, and c CCL20 levels in response to live M. mulieris exposure; d IL-6, e IL-8, and f CCL20 levels in response to BFS M. mulieris exposure; g IL-6, h IL-8, and i CCL20 levels in response to bEV M. mulieris exposure. The inhibitors for hTLR2 and hTLR5 are written as TLR2i and TLR5i. Bar plots represent the mean, the error bars for the standard deviation, and the dots represent the technical replicate (n = 3). One-way ANOVA was used, followed by Tukey’s multiple comparison test, with statistical significance denoted by “*” (p < 0.05), “**” (p < 0.01), “***” (p < 0.001), “****” (p < 0.0001).

Back to article page