Table 1 Comparison of clinicopathologic factors based on HER2 status after 1:2 propensity score matching
From: Prognostic difference between early breast cancer patients with HER2 low and HER2 zero status
Variables | All patients (N = 1152) | p | |
|---|---|---|---|
HER2-zero (N = 707) | HER2-low (N = 445) | ||
Age, years (mean ± SD) | 50.9 ± 10.6 | 51.4 ± 10.0 | 0.469 |
Breast surgery | 0.153 | ||
Breast conservation | 421 (59.5) | 274 (61.6) | |
Mastectomy | 286 (40.5) | 169 (38.0) | |
Unknown | – | 2 (0.4) | |
Pathologic tumor stage | 0.999 | ||
T1 | 417 (59.0) | 262 (58.9) | |
T2 | 255 (36.1) | 161 (36.2) | |
T3 | 35 (4.9) | 22 (4.9) | |
Pathologic nodal stage | 0.952 | ||
N0 | 478 (67.6) | 305 (68.5) | |
N1 | 149 (21.1) | 94 (21.1) | |
N2 | 45 (6.4) | 27 (6.1) | |
N3 | 35 (4.9) | 19 (4.3) | |
Hormone receptor status | 0.556 | ||
Positive | 557 (78.8) | 357 (80.2) | |
Negative | 150 (21.2) | 88 (19.8) | |
Histologic grade | 0.638 | ||
1 | 158 (22.3) | 88 (19.8) | |
2 | 327 (46.3) | 217 (48.8) | |
3 | 187 (26.4) | 114 (25.6) | |
Unknown | 35 (5.0) | 26 (5.8) | |
Chemotherapy | 0.101 | ||
Yes | 655 (92.6) | 400 (89.9) | |
No | 52 (7.4) | 45 (10.1) | |
Radiotherapy | 0.728 | ||
Yes | 482 (68.2) | 299 (67.2) | |
No | 225 (31.8) | 146 (32.8) | |
Hormone therapy | 0.862 | ||
Yes | 545 (77.1) | 345 (77.5) | |
No | 162 (22.9) | 100 (22.5) | |
