Fig. 1: Invasive disease-free survival in patients with microinvasive, lymph node-negative, HER2-positive breast cancer: stratification by number of microinvasive foci (1–4 vs. ≥5) and by receipt of adjuvant chemotherapy and/or HER2-targeted therapy (CT and/or H2TT) among patients with ≥5 foci of microinvasion.

Comparison of iDFS between (a) patients with 1–4 vs. ≥5 microinvasive foci; (b) patients with ≥5 foci who received (yes) vs. did not receive (no) adjuvant CT and/or H2TT.