Table 1 Age at diagnosis and age-standardized participant characteristics according to first post-diagnostic aspirin use among 10,705 women diagnosed with breast cancer in the NHS and NHSII
From: Regular aspirin use, breast tumor characteristics and long-term breast cancer survival
Participant characteristics | Post-diagnostic | |
|---|---|---|
Regular aspirin use (≥2 days/week) | ||
Nonuser N = 7122 | Aspirin user N = 3583 | |
Age at diagnosis (years) [mean (SD)] | 58.3 (10.7) | 64.3 (9.8) |
Year of diagnosis (years) [mean (SD)] | 2000 (9) | 2001 (9) |
White [%] | 97% | 98% |
Pre-diagnostic regular aspirin use ( ≥2 days/week) [%] | 12% | 64% |
BMI (kg/m2) [mean (SD)] | 25.9 (4.9) | 26.3 (5.0) |
Current smoker [%] | 8% | 9% |
Physical activity (MET-h/week) [mean (SD)] | 26.3 (30.7) | 24.5 (28.2) |
Post-menopausal at diagnosis [%] | 72 | 72 |
Parous [%] | 90 | 89 |
Ever use of oral contraceptives [%] | 31 | 33 |
Ever use of hormone replacement therapy [%] | 48 | 51 |
Estrogen receptor positive [%] | 79 | 80 |
Progesterone receptor-positive [%] | 67 | 69 |
HER2 positive [%] | 12 | 11 |
Disease stage at diagnosis [%] | ||
I | 56 | 61 |
II | 32 | 31 |
III | 12 | 8 |
Treatment [%] | ||
Hormone therapy | 70 | 72 |
Chemotherapy | 4% | 44 |
Radiation | 58 | 60 |
History of physician-diagnosed myocardial infarction [%] | 1 | 2 |
History of physician-diagnosed stroke [%] | 1 | 2 |
History of physician-diagnosed rheumatoid arthritis [%] | 2 | 1 |
History of self-reported angina [%] | 3 | 7 |
