Fig. 1: Association of TILs with treatment response. | npj Breast Cancer

Fig. 1: Association of TILs with treatment response.

From: Association of potential biomarkers with clinical outcomes in metastatic triple-negative breast cancer treated with pembrolizumab or chemotherapy

Fig. 1

a TIL levels in responders and nonresponders. b Overall survival by median TIL cutpoints of < 5% and ≥ 5%. TILs are plotted on a square-root scale. The median TIL level was 20% among responders in the pembrolizumab group and 5% among nonresponders in the pembrolizumab group. Median TIL level was 5% among responders and nonresponders in the chemotherapy group. In these boxplots, the whiskers extend no further than 1.5 times the interquartile range; dots represent values that fall outside 1.5 times the interquartile range. Responses evaluated by blinded independent central review per RECIST version 1.1. HR hazard ratio, RECIST Response Evaluation Criteria in Solid Tumors, TIL tumor-infiltrating lymphocyte.

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