Fig. 2: Association of TcellinfGEP with treatment response.

a TcellinfGEP scores in responders and nonresponders. b AUROC analysis of the association between TcellinfGEP score and objective response rate. c OS by TcellinfGEP score with a 1st tertile cutpoint (< 1st tertile vs ≥ 1st tertile). In these boxplots, the whiskers extend no further than 1.5 times the interquartile range; dots represent values that fall outside 1.5 times the interquartile range. aResponders include participants who had a complete or partial response per RECIST version 1.1. AUC area under the curve, AUROC area under the receiver operating characteristic curve, HR hazard ratio, RECIST Response Evaluation Criteria in Solid Tumors, TcellinfGEP T-cell‒inflamed gene expression profile, TPC treatment of physician’s choice chemotherapy.