Fig. 1: Role of BSG in surpassing the hallmarks of cancer.
From: The pleiotropic roles of non-hormonal receptor basigin and regulatory microRNAs in breast cancer
The Hallmarks of cancer, first introduced by Hanahan and Weinberg in 200095 and updated in 201194 and 202293 provide a useful way of framing the various roles BSG plays in the oncogenic environment. Notably, BSG influences non-mutational epigenetic reprogramming, invasion and metastasis, angiogenesis, cellular energetics, and phenotypic plasticity. These hallmarks, highlighted amongst the current hallmarks, form the basis of this review. Created in BioRender. Richard, V. (2025) https://BioRender.com/8ttjnxe.
