Table 1 Novel loci discovered in MTAG for atrial fibrillation, coronary artery disease and heart failure
Single T. | Multi T. | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genomic Locus | rsID | GRCh37 position | start | end | EA | non-EA | EAF | Z-score | P- value | Z-score | P- value | Mapped gene | Previously reported |
Atrial fibrillation | |||||||||||||
1 | rs2903492 | 2:624,678 | 408,713 | 653,874 | A | G | 0.81 | 4.180 | 2.7 x 10-5 | 7.247 | 4.3 x 10-13 | SH3YL1 | |
2 | rs6841049 | 4:83,910,712 | 83,722,128 | 83,998,642 | T | G | 0.43 | 5.448 | 6.0 x 10-8 | 5.863 | 4.5 x 10-9 | LIN54 | |
3 | rs78677597 | 6:100,610,044 | 100,600,097 | 100,629,078 | C | A | 0.23 | 5.222 | 1.8 x 10-7 | 5.992 | 2.1 x 10-9 | SIM1 | |
4 | rs11153653 | 6:117,529,850 | 117,471,951 | 117,529,850 | C | T | 0.45 | 5.176 | 2.5 x 10-7 | 5.468 | 4.6 x 10-8 | VGLL2 | * |
5 | rs563452 | 6:124,933,144 | 124,896,441 | 124,945,602 | T | C | 0.18 | 4.942 | 7.3 x 10-7 | 5.878 | 4.2 x 10-9 | NKAIN2 | |
6 | rs596878 | 6:140,286,236 | 140,263,827 | 140,299,541 | A | C | 0.55 | 4.761 | 2.0 x 10-6 | 5.453 | 4.9 x 10-8 | - | |
7 | rs6465867 | 7:77,497,472 | 77,237,390 | 77,598,538 | C | T | 0.48 | 4.134 | 3.4 x 10-5 | 5.568 | 2.6 x 10-8 | TMEM60 | |
8 | rs1330303 | 9:16,715,826 | 16,713,666 | 16,762,034 | T | C | 0.36 | 4.686 | 2.5 x 10-6 | 5.469 | 4.5 x 10-8 | BNC2 | |
9 | rs76895963 | 12:4,384,844 | 4,384,844 | 4,384,844 | G | T | 0.02 | 5.284 | 1.3 x 10-7 | 5.730 | 1.0 x 10-8 | CCND2 | |
10 | rs116904997 | 12:120,668,534 | 120,163,274 | 120,698,731 | G | A | 0.98 | 5.328 | 9.4 x 10-8 | 6.007 | 1.9 x 10-9 | PXN | |
11 | rs4883571 | 12:133,091,614 | 133,049,093 | 133,115,411 | A | G | 0.39 | 5.348 | 1.1 x 10-7 | 5.559 | 2.7 x 10-8 | FBRSL1 | * |
12 | rs2370982 | 14:79,890,677 | 79,833,494 | 79,945,162 | T | C | 0.21 | 4.293 | 1.6 x 10-5 | 5.945 | 2.8 x 10-9 | NRXN3 | |
13 | rs11150675 | 16:28,980,531 | 28,829,228 | 29,008,079 | G | A | 0.65 | 4.743 | 2.4 x 10-6 | 5.898 | 3.7 x 10-9 | SPNS1 | |
14 | rs62048402 | 16:53,803,223 | 53,797,565 | 53,848,561 | A | G | 0.41 | 4.373 | 1.4 x 10-5 | 9.203 | 3.5 x 10-20 | FTO-IRX3-IRX5 | * |
15 | rs2209073 | 17:2,205,664 | 2,087,605 | 2,216,258 | G | A | 0.39 | 4.809 | 1.6 x 10-6 | 5.501 | 3.8 x 10-8 | SRR | |
16 | rs1429935 | 18:21,086,216 | 21,075,441 | 21,165,409 | A | C | 0.51 | 3.403 | 6.3 x 10-4 | 5.787 | 7.2 x 10-9 | RMC1 | |
17 | rs12967135 | 18:57,849,023 | 57,732,418 | 57,913,434 | A | G | 0.24 | 2.351 | 1.9 x 10-2 | 6.368 | 1.9 x 10-10 | MC4R | |
18 | rs2974231 | 19:48,170,757 | 48,127,103 | 48,170,757 | A | G | 0.56 | 5.116 | 3.4 x 10-7 | 5.613 | 2.0 x 10-8 | NOP53 | |
19 | rs9981470 | 21:36,822,544 | 36,822,544 | 36,843,100 | T | C | 0.34 | 5.370 | 8.9 x 10-8 | 5.498 | 3.9 x 10-8 | CBR3 | |
Coronary artery disease | |||||||||||||
1 | rs263533 | 1:2,163,568 | 2,149,292 | 2,205,581 | C | T | 0.57 | 4.182 | 2.9 x 10-5 | 5.650 | 1.6 x 10-8 | FAAP20 | * |
2 | rs2493296 | 1:3,327,032 | 3,320,476 | 3,330,884 | T | C | 0.13 | 3.473 | 5.2 x 10-4 | 6.261 | 3.8 x 10-10 | PRDM16 | * |
3 | rs880315 | 1:10,796,866 | 10,789,634 | 10,802,977 | C | T | 0.34 | 2.897 | 3.8 x 10-3 | 7.505 | 6.1 x 10-14 | CASZ1 | |
4 | rs55857306 | 1:11,895,795 | 11,827,796 | 11,910,462 | G | A | 0.85 | 2.590 | 9.6 x 10-3 | 7.656 | 1.9 x 10-14 | CLCN6 | * |
5 | rs12091750 | 1:16,042,766 | 15,907,354 | 16,050,470 | T | C | 0.74 | 3.473 | 5.2 x 10-4 | 6.130 | 8.8 x 10-10 | PLEKHM2 | |
6 | rs28605759 | 1:38,399,816 | 38,386,727 | 38,463,504 | A | G | 0.43 | 4.535 | 5.8 x 10-6 | 7.134 | 9.8 x 10-13 | INPP5B | * |
7 | rs6587520 | 1:150,709,723 | 150,534,368 | 150,958,977 | T | C | 0.48 | 4.841 | 1.3 x 10-6 | 5.656 | 1.6 x 10-8 | CTSS | * |
8 | rs699 | 1:230,845,794 | 230,828,348 | 230,879,952 | G | A | 0.42 | 3.812 | 1.4 x 10-4 | 6.872 | 6.4 x 10-12 | AGT | * |
9 | rs1275988 | 2:26,914,364 | 26,911,509 | 26,932,796 | C | T | 0.42 | 0.887 | 3.8 x 10-1 | 5.581 | 2.4 x 10-8 | CIB4 | |
10 | rs7564469 | 2:145,258,445 | 145,256,508 | 145,270,592 | C | T | 0.18 | 4.646 | 3.4 x 10-6 | 5.933 | 3.0 x 10-9 | ZEB2 | * |
11 | rs34611819 | 2:164,934,709 | 164,699,934 | 165,132,714 | G | A | 0.82 | 4.421 | 1.0 x 10-5 | 8.138 | 4.0 x 10-16 | FIGN | * |
12 | rs2161967 | 2:218,680,529 | 218,667,372 | 218,695,848 | T | G | 0.46 | 4.521 | 6.2 x 10-6 | 7.061 | 1.7 x 10-12 | TNS1 | * |
13 | rs2972146 | 2:227,100,698 | 227,020,653 | 227,199,263 | T | G | 0.65 | 5.407 | 6.5 x 10-8 | 7.077 | 1.5 x 10-12 | IRS1 | * |
14 | rs748431 | 3:14,928,077 | 14,877,535 | 14,958,126 | G | T | 0.39 | 4.915 | 9.0 x 10-7 | 7.360 | 1.8 x 10-13 | FGD5 | * |
15 | rs9839447 | 3:48,194,667 | 47,587,905 | 48,379,787 | C | T | 0.65 | 2.646 | 8.1 x 10-3 | 5.620 | 1.9 x 10-8 | ZNF589 | * |
16 | rs7615099 | 3:53,143,901 | 52,970,877 | 53,174,638 | A | G | 0.69 | 3.695 | 2.2 x 10-4 | 5.572 | 2.5 x 10-8 | RFT1 | |
17 | rs35432681 | 3:133,966,291 | 133,818,550 | 134,012,711 | C | T | 0.37 | 3.020 | 2.5 x 10-3 | 5.482 | 4.2 x 10-8 | CEP63 | |
18 | rs448378 | 3:169,100,899 | 168,785,191 | 169,192,040 | G | A | 0.48 | 2.635 | 8.4 x 10-3 | 5.892 | 3.8 x 10-9 | MECOM | * |
19 | rs2061456 | 4:17,998,426 | 17,792,869 | 18,025,484 | C | A | 0.75 | 3.321 | 9.0 x 10-4 | 5.637 | 1.7 x 10-8 | DCAF16 | |
20 | rs7687234 | 4:26,808,829 | 26,783,453 | 26,812,737 | T | C | 0.41 | 2.763 | 5.7 x 10-3 | 5.504 | 3.7 x 10-8 | STIM2 | |
21 | rs1565115 | 4:38,361,626 | 38,334,213 | 38,372,504 | C | T | 0.59 | 3.260 | 1.1 x 10-3 | 5.732 | 9.9 x 10-9 | KLF3 | |
22 | rs4859683 | 4:77,419,073 | 77,392,092 | 77,437,749 | C | T | 0.36 | 3.706 | 2.1 x 10-4 | 6.257 | 3.9 x 10-10 | SHROOM3 | * |
23 | rs4637383 | 4:120,305,966 | 120,158,685 | 120,320,771 | A | G | 0.26 | 3.971 | 7.2 x 10-5 | 5.478 | 4.3 x 10-8 | FABP2 | * |
24 | rs7678555 | 4:120,909,501 | 120,897,847 | 120,968,070 | C | A | 0.28 | 5.267 | 1.4 x 10-7 | 6.277 | 3.5 x 10-10 | MAD2L1 | * |
25 | rs10006310 | 4:146,809,998 | 146,756,490 | 146,821,725 | T | G | 0.53 | 4.645 | 3.5 x 10-6 | 6.346 | 2.2 x 10-10 | ZNF827 | * |
26 | rs869396 | 4:169,688,000 | 169,682,578 | 169,749,787 | C | A | 0.52 | 4.775 | 1.9 x 10-6 | 6.759 | 1.4 x 10-11 | CBR4 | * |
27 | rs1173727 | 5:32,830,521 | 32,689,773 | 32,832,474 | C | T | 0.60 | 1.340 | 1.8 x 10-1 | 7.208 | 5.7 x 10-13 | NPR3 | |
28 | rs28650790 | 5:55,861,464 | 55,851,531 | 55,870,395 | T | C | 0.18 | 4.983 | 6.4 x 10-7 | 6.824 | 8.8 x 10-12 | MAP3K1 | * |
29 | rs6865322 | 5:127,877,745 | 127,646,426 | 128,053,546 | A | G | 0.32 | 4.023 | 5.8 x 10-5 | 7.098 | 1.3 x 10-12 | FBN2 | * |
30 | rs3776307 | 5:142,494,165 | 142,494,165 | 142,507,651 | G | A | 0.43 | 4.434 | 9.4 x 10-6 | 5.613 | 2.0 x 10-8 | ARHGAP26 | * |
31 | rs7708926 | 5:157,837,767 | 157,802,270 | 157,909,469 | T | C | 0.58 | 3.516 | 4.5 x 10-4 | 7.071 | 1.5 x 10-12 | - | |
32 | rs9501744 | 6:1,617,143 | 1,616,265 | 1,624,512 | C | T | 0.87 | 4.879 | 1.1 x 10-6 | 5.818 | 6.0 x 10-9 | FOXC1 | * |
33 | rs56336142 | 6:39,134,099 | 39,124,448 | 39,187,886 | T | C | 0.80 | 5.112 | 3.3 x 10-7 | 5.846 | 5.0 x 10-9 | SAYSD1 | * |
34 | rs1214752 | 6:43,396,325 | 43,260,011 | 43,408,005 | C | T | 0.50 | 4.658 | 3.3 x 10-6 | 6.326 | 2.5 x 10-10 | CRIP3 | |
35 | rs6905288 | 6:43,758,873 | 43,757,082 | 43,760,327 | A | G | 0.57 | 4.655 | 3.3 x 10-6 | 5.795 | 6.8 x 10-9 | VEGFA | * |
36 | rs9443621 | 6:79,576,499 | 79,345,249 | 79,823,541 | G | A | 0.50 | 3.398 | 6.8 x 10-4 | 6.177 | 6.5 x 10-10 | PHIP | |
37 | rs11756347 | 6:127,177,470 | 126,642,219 | 127,246,737 | G | A | 0.43 | 1.975 | 4.8 x 10-2 | 6.660 | 2.7 x 10-11 | RSPO3 | * |
38 | rs62434123 | 6:150,999,464 | 150,975,312 | 151,034,312 | C | T | 0.92 | 3.477 | 5.1 x 10-4 | 6.980 | 3.0 x 10-12 | PLEKHG1 | * |
39 | rs10262140 | 7:27,256,464 | 27,229,119 | 27,281,157 | C | T | 0.91 | 0.987 | 3.2 x 10-1 | 5.500 | 3.8 x 10-8 | HOXA9 | |
40 | rs62481856 | 7:106,412,082 | 106,405,642 | 106,419,296 | A | G | 0.21 | 2.502 | 1.2 x 10-2 | 7.663 | 1.8 x 10-14 | CCDC71L | * |
41 | rs112370447 | 7:107,176,780 | 106,796,537 | 107,304,628 | T | C | 0.28 | 4.905 | 9.6 x 10-7 | 5.785 | 7.3 x 10-9 | COG5 | * |
42 | rs9640375 | 7:139,737,344 | 139,717,178 | 139,761,248 | C | T | 0.78 | 5.025 | 5.2 x 10-7 | 6.228 | 4.7 x 10-10 | PARP12 | * |
43 | rs718741 | 8:10,614,384 | 10,576,753 | 10,732,050 | C | T | 0.42 | 2.896 | 3.8 x 10-3 | 6.519 | 7.1 x 10-11 | BLK | |
44 | rs80302977 | 8:19,934,339 | 19,815,256 | 19,943,308 | T | C | 0.93 | 5.056 | 4.4 x 10-7 | 6.473 | 9.6 x 10-11 | LPL | * |
45 | rs111245230 | 9:113,169,775 | 113,122,387 | 113,250,200 | C | T | 0.04 | 4.931 | 8.3 x 10-7 | 6.781 | 1.2 x 10-11 | SVEP1 | * |
46 | rs11257613 | 10:12,284,392 | 12,241,815 | 12,308,889 | G | A | 0.49 | 4.287 | 1.8 x 10-5 | 5.838 | 5.3 x 10-9 | NUDT5 | * |
47 | rs150446556 | 10:18,715,942 | 18,681,659 | 18,774,722 | T | C | 0.73 | 2.798 | 5.2 x 10-3 | 7.841 | 4.5 x 10-15 | NSUN6 | |
48 | rs72831343 | 10:63,515,681 | 63,424,211 | 63,552,598 | T | G | 0.87 | 2.391 | 1.7 x 10-2 | 6.684 | 2.3 x 10-11 | CABCOCO1 | |
49 | rs7098414 | 10:82,214,586 | 82,015,725 | 82,230,146 | A | C | 0.26 | 4.699 | 2.7 x 10-6 | 6.641 | 3.1 x 10-11 | ANXA11 | |
50 | rs603424 | 10:102,075,479 | 102,075,479 | 102,075,479 | A | G | 0.21 | 3.769 | 1.7 x 10-4 | 5.638 | 1.7 x 10-8 | PKD2L1 | * |
51 | rs569550 | 11:1,887,068 | 1,884,342 | 1,949,470 | G | T | 0.39 | 1.299 | 1.9 x 10-1 | 6.472 | 9.6 x 10-11 | TNNT3 | |
52 | rs7926712 | 11:13,303,085 | 13,267,867 | 13,352,405 | G | A | 0.69 | 5.318 | 1.1 x 10-7 | 6.602 | 4.1 x 10-11 | ARNTL | * |
53 | rs5219 | 11:17,409,572 | 17,368,013 | 17,421,886 | T | C | 0.36 | 2.440 | 1.5 x 10-2 | 5.687 | 1.3 x 10-8 | KCNJ11 | |
54 | rs58385891 | 11:46,348,663 | 46,348,663 | 46,348,663 | A | G | 0.17 | 4.165 | 3.1 x 10-5 | 5.613 | 2.0 x 10-8 | DGKZ | |
55 | rs4597030 | 11:48,176,573 | 47,385,350 | 51,446,535 | A | G | 0.73 | 4.114 | 3.9 x 10-5 | 6.670 | 2.6 x 10-11 | PTPRJ | |
56 | rs11600896 | 11:56,058,535 | 55,129,721 | 56,429,063 | T | C | 0.14 | 4.333 | 1.5 x 10-5 | 5.773 | 7.8 x 10-9 | OR8H1 | |
57 | rs12801636 | 11:65,391,317 | 65,365,077 | 65,566,719 | G | A | 0.77 | 4.476 | 7.8 x 10-6 | 6.846 | 7.6 x 10-12 | SIPA1 | * |
58 | rs604723 | 11:100,610,546 | 100,509,745 | 100,692,566 | C | T | 0.70 | 3.886 | 1.0 x 10-4 | 9.015 | 2.0 x 10-19 | ARHGAP42 | * |
59 | rs4347355 | 11:107,075,997 | 107,053,437 | 107,140,077 | G | A | 0.46 | 3.360 | 7.8 x 10-4 | 6.123 | 9.2 x 10-10 | CWF19L2 | * |
60 | rs2078339 | 12:20,161,168 | 19,955,874 | 20,247,540 | A | G | 0.71 | 4.645 | 3.4 x 10-6 | 6.942 | 3.9 x 10-12 | PDE3A | * |
61 | rs9583531 | 13:111,385,161 | 111,351,369 | 111,406,396 | G | T | 0.18 | 4.455 | 8.5 x 10-6 | 5.923 | 3.2 x 10-9 | ING1 | * |
62 | rs9549328 | 13:113,636,156 | 113,613,383 | 113,659,706 | T | C | 0.23 | 3.651 | 2.6 x 10-4 | 5.556 | 2.8 x 10-8 | MCF2L | * |
63 | rs710292 | 14:98,535,770 | 98,532,540 | 98,628,943 | G | T | 0.41 | 3.414 | 6.5 x 10-4 | 5.514 | 3.5 x 10-8 | - | |
64 | rs11854147 | 15:75,052,771 | 75,031,521 | 75,238,663 | T | C | 0.34 | 2.737 | 6.2 x 10-3 | 6.284 | 3.3 x 10-10 | CSK | * |
65 | rs2083460 | 15:89,574,484 | 89,562,814 | 89,580,299 | T | C | 0.89 | 5.268 | 1.4 x 10-7 | 5.870 | 4.4 x 10-9 | ABHD2 | * |
66 | rs247616 | 16:56,989,590 | 56,985,514 | 57,001,274 | C | T | 0.68 | 4.894 | 1.0 x 10-6 | 6.867 | 6.6 x 10-12 | NLRC5 | * |
67 | rs3863446 | 16:75,385,735 | 75,234,273 | 75,519,917 | A | G | 0.58 | 4.868 | 1.1 x 10-6 | 8.295 | 1.1 x 10-16 | CFDP1 | * |
68 | rs12926550 | 16:81,510,155 | 81,510,155 | 81,513,871 | G | A | 0.69 | 3.501 | 4.7 x 10-4 | 5.503 | 3.7 x 10-8 | CMIP | * |
69 | rs903162 | 17:2,092,200 | 1,957,597 | 2,207,236 | A | G | 0.32 | 5.330 | 1.0 x 10-7 | 6.737 | 1.6 x 10-11 | SRR | * |
70 | rs16960744 | 17:17,755,259 | 17,519,037 | 18,029,857 | A | G | 0.41 | 4.448 | 8.8 x 10-6 | 5.888 | 3.9 x 10-9 | SREBF1 | * |
71 | rs3744760 | 17:43,195,981 | 43,101,281 | 43,196,584 | C | T | 0.29 | 2.187 | 2.9 x 10-2 | 5.729 | 1.0 x 10-8 | DCAKD | |
72 | rs17608766 | 17:45,013,271 | 44,888,742 | 45,244,074 | C | T | 0.13 | 3.431 | 6.1 x 10-4 | 8.120 | 4.7 x 10-16 | GOSR2 | * |
73 | rs4643373 | 17:47,123,423 | 46,835,629 | 47,514,127 | T | C | 0.72 | 4.861 | 1.2 x 10-6 | 6.987 | 2.8 x 10-12 | TTLL6 | * |
74 | rs6504218 | 17:62,408,299 | 62,364,965 | 62,410,328 | G | A | 0.52 | 4.909 | 9.4 x 10-7 | 6.594 | 4.3 x 10-11 | PECAM1 | * |
75 | rs1135889 | 17:73,926,121 | 73,826,406 | 73,953,404 | C | A | 0.78 | 3.701 | 2.2 x 10-4 | 5.589 | 2.3 x 10-8 | FBF1 | * |
76 | rs7220955 | 17:76,700,063 | 76,661,269 | 76,833,916 | G | A | 0.45 | 3.193 | 1.4 x 10-3 | 5.980 | 2.2 x 10-9 | USP36 | |
77 | rs7227492 | 18:772,064 | 769,958 | 811,700 | T | C | 0.80 | 2.838 | 4.5 x 10-3 | 5.563 | 2.7 x 10-8 | ENOSF1 | |
78 | rs116843064 | 19:8,429,323 | 8,429,323 | 8,429,323 | G | A | 0.98 | 5.135 | 2.9 x 10-7 | 5.973 | 2.3 x 10-9 | ANGPTL4 | * |
79 | rs7246865 | 19:17,219,105 | 17,156,501 | 17,228,554 | A | G | 0.29 | 3.595 | 3.3 x 10-4 | 6.026 | 1.7 x 10-9 | HAUS8 | * |
80 | rs28403253 | 19:17,858,360 | 17,826,412 | 17,875,755 | A | G | 0.47 | 4.317 | 1.6 x 10-5 | 5.485 | 4.1 x 10-8 | FCHO1 | * |
81 | rs73045269 | 19:41,825,191 | 41,731,175 | 41,877,313 | T | C | 0.15 | 5.235 | 1.7 x 10-7 | 6.161 | 7.2 x 10-10 | TGFB1 | * |
82 | rs7273599 | 20:10,971,744 | 10,936,029 | 11,009,079 | C | T | 0.27 | 3.564 | 3.7 x 10-4 | 7.109 | 1.2 x 10-12 | JAG1 | |
83 | rs56313611 | 20:47,456,856 | 47,409,390 | 47,495,767 | C | T | 0.87 | 4.830 | 1.4 x 10-6 | 6.914 | 4.7 x 10-12 | ZNFX1 | * |
84 | rs259983 | 20:57,735,457 | 57,674,273 | 57,820,502 | C | A | 0.14 | 4.681 | 2.9 x 10-6 | 8.693 | 3.5 x 10-18 | NELFCD | * |
85 | rs6062541 | 20:62,449,320 | 62,402,072 | 62,761,699 | C | T | 0.77 | 3.295 | 9.9 x 10-4 | 5.704 | 1.2 x 10-8 | TPD52L2 | * |
86 | rs1882961 | 21:16,556,367 | 16,532,660 | 16,560,118 | T | C | 0.30 | 3.682 | 2.3 x 10-4 | 5.729 | 1.0 x 10-8 | NRIP1 | |
87 | rs66654103 | 21:30,603,775 | 30,519,457 | 30,608,884 | G | A | 0.18 | 4.691 | 2.8 x 10-6 | 6.227 | 4.8 x 10-10 | MAP3K7CL | * |
88 | rs2838351 | 21:45,110,784 | 44,765,581 | 45,133,948 | G | A | 0.59 | 4.029 | 5.6 x 10-5 | 6.186 | 6.2 x 10-10 | RRP1B | |
89 | rs2238792 | 22:19,983,213 | 19,960,184 | 20,004,311 | T | C | 0.29 | 3.843 | 1.2 x 10-4 | 5.467 | 4.6 x 10-8 | ARVCF | * |
A3 | rs10167465 | 2:43,397,176 | 43,369,101 | 43,397,614 | G | A | 0.37 | 4.820 | 1.4 x 10-6 | 5.816 | 6.0 x 10-9 | ZFP36L2 | |
A4 | rs12693302 | 2:183,211,443 | 183,182,776 | 183,263,753 | G | A | 0.38 | 5.121 | 3.0 x 10-7 | 5.903 | 3.6 x 10-9 | PDE1A | * |
A5 | rs62172372 | 2:188,242,369 | 188,003,118 | 188,381,367 | A | G | 0.79 | 5.410 | 6.3 x 10-8 | 5.538 | 3.1 x 10-8 | CALCRL | * |
A7 | rs59950280 | 4:3,452,345 | 3,443,931 | 3,482,678 | A | G | 0.34 | 5.346 | 9.0 x 10-8 | 5.814 | 6.1 x 10-9 | DOK7 | * |
A8 | rs1434538 | 4:96,066,672 | 95,937,284 | 96,101,156 | C | T | 0.46 | 5.016 | 5.3 x 10-7 | 5.554 | 2.8 x 10-8 | BMPR1B | * |
A10 | rs9799914 | 5:122,671,476 | 122,650,224 | 122,680,189 | G | A | 0.51 | 4.966 | 6.8 x 10-7 | 5.532 | 3.2 x 10-8 | CSNK1G3 | |
A11 | rs39929 | 5:156,123,651 | 155,949,781 | 156,145,816 | A | G | 0.81 | 5.417 | 6.1 x 10-8 | 6.044 | 1.5 x 10-9 | SGCD | * |
A13 | rs3829964 | 6:36,644,498 | 36,616,366 | 36,648,920 | T | C | 0.52 | 5.235 | 1.7 x 10-7 | 5.914 | 3.3 x 10-9 | CDKN1A | * |
A15 | rs1534298 | 6:152,823,054 | 152,775,358 | 152,871,405 | A | G | 0.29 | 4.891 | 1.0 x 10-6 | 5.458 | 4.8 x 10-8 | SYNE1 | |
A16 | rs1047763 | 7:7,283,569 | 7,223,416 | 7,292,458 | A | G | 0.17 | 5.284 | 1.3 x 10-7 | 5.826 | 5.7 x 10-9 | C1GALT1 | |
A19 | rs2155939 | 8:102,847,202 | 102,754,922 | 102,916,321 | A | G | 0.73 | 5.119 | 3.1 x 10-7 | 5.698 | 1.2 x 10-8 | NCALD | * |
A22 | rs10763918 | 10:33,516,014 | 33,476,141 | 33,519,019 | T | C | 0.33 | 4.991 | 6.0 x 10-7 | 5.535 | 3.1 x 10-8 | NRP1 | |
A23 | rs7903146 | 10:114,758,349 | 114,749,734 | 114,817,009 | T | C | 0.29 | 5.407 | 6.4 x 10-8 | 6.137 | 8.4 x 10-10 | TCF7L2 | * |
A25 | rs177544 | 11:16,925,046 | 16,481,576 | 16,946,101 | T | C | 0.13 | 4.532 | 5.8 x 10-6 | 5.685 | 1.3 x 10-8 | PIK3C2A | * |
A26 | rs2625388 | 11:43,611,826 | 43,601,860 | 43,810,235 | A | G | 0.55 | 4.745 | 2.1 x 10-6 | 5.509 | 3.6 x 10-8 | HSD17B12 | |
A29 | rs4762753 | 12:20,579,969 | 20,578,881 | 20,587,192 | G | T | 0.79 | 5.033 | 4.8 x 10-7 | 5.744 | 9.3 x 10-9 | PDE3A | |
A30 | rs3959554 | 15:41,443,924 | 41,252,202 | 41,556,015 | G | A | 0.41 | 5.118 | 3.1 x 10-7 | 5.848 | 5.0 x 10-9 | CHP1 | * |
A32 | rs4551990 | 15:86,015,287 | 85,530,987 | 86,082,147 | A | C | 0.43 | 5.261 | 1.4 x 10-7 | 5.721 | 1.1 x 10-8 | AKAP13 | |
A33 | rs9745736 | 16:4,905,691 | 4,847,317 | 4,952,598 | A | G | 0.52 | 4.417 | 1.0 x 10-5 | 5.759 | 8.4 x 10-9 | PPL | |
A34 | rs76954792 | 17:30,033,514 | 30,023,645 | 30,033,514 | T | C | 0.23 | 5.233 | 1.7 x 10-7 | 5.877 | 4.2 x 10-9 | COPRS | * |
A35 | rs16968377 | 17:36,942,396 | 36,914,877 | 36,942,396 | C | T | 0.06 | 5.013 | 5.4 x 10-7 | 5.656 | 1.6 x 10-8 | PIP4K2B | |
A37 | rs12185519 | 19:4,967,739 | 4,916,317 | 5,024,099 | T | C | 0.20 | 5.189 | 2.1 x 10-7 | 5.771 | 7.9 x 10-9 | ARRDC5 | * |
A38 | rs3745318 | 19:16,436,262 | 16,415,993 | 16,443,718 | T | C | 0.25 | 5.403 | 6.5 x 10-8 | 5.918 | 3.3 x 10-9 | KLF2 |
Heart Failure | |||||||||||||
1 | rs28605759 | 1:38,399,816 | 38,386,727 | 38,461,821 | A | G | 0.46 | 3.613 | 3.1 x 10-4 | 6.019 | 1.8 x 10-9 | INPP5B | |
2 | rs17391905 | 1:51,546,140 | 50,873,429 | 52,037,756 | G | T | 0.03 | 3.788 | 1.6 x 10-4 | 5.749 | 9.0 x 10-9 | TXNDC12 | * |
3 | rs72664353 | 1:57,001,898 | 56,912,610 | 57,020,650 | C | T | 0.91 | 3.764 | 1.6 x 10-4 | 7.160 | 8.1 x 10-13 | PLPP3 | |
4 | rs6689306 | 1:154,395,946 | 154,395,125 | 154,428,505 | A | G | 0.41 | 2.925 | 3.5 x 10-3 | 7.582 | 3.4 x 10-14 | IL6R | |
5 | rs11264280 | 1:154,862,952 | 154,812,059 | 154,948,327 | T | C | 0.33 | 3.000 | 2.6 x 10-3 | 7.084 | 1.4 x 10-12 | ADAM15 | |
6 | rs144870427 | 1:170,206,419 | 170,170,094 | 170,206,419 | C | T | 0.04 | 3.660 | 2.5 x 10-4 | 6.235 | 4.5 x 10-10 | NTMT2 | |
7 | rs577676 | 1:170,587,340 | 170,560,604 | 170,642,899 | C | T | 0.56 | 1.848 | 6.6 x 10-2 | 7.177 | 7.1 x 10-13 | GORAB | |
8 | rs17163313 | 1:222,799,625 | 222,779,187 | 222,940,523 | G | T | 0.70 | 4.000 | 6.7 x 10-5 | 6.873 | 6.3 x 10-12 | MIA3 | |
9 | rs12714145 | 2:85,787,341 | 85,725,354 | 85,812,784 | T | C | 0.40 | 2.913 | 3.4 x 10-3 | 6.085 | 1.2 x 10-9 | GGCX | |
10 | rs7564469 | 2:145,258,445 | 145,256,508 | 145,270,592 | C | T | 0.16 | 3.514 | 4.4 x 10-4 | 5.676 | 1.4 x 10-8 | ZEB2 | |
11 | rs295129 | 2:201,229,473 | 201,071,942 | 201,244,261 | G | A | 0.44 | 4.114 | 4.1 x 10-5 | 7.182 | 6.9 x 10-13 | SPATS2L | * |
12 | rs72932590 | 2:203,884,308 | 203,639,395 | 204,196,618 | C | A | 0.12 | 2.127 | 3.4 x 10-2 | 6.127 | 9.0 x 10-10 | NBEAL1 | |
13 | rs17843797 | 3:124,453,022 | 124,438,586 | 124,501,821 | G | T | 0.12 | 2.645 | 7.9 x 10-3 | 5.671 | 1.4 x 10-8 | UMPS | |
14 | rs10938398 | 4:45,186,139 | 45,165,650 | 45,187,622 | A | G | 0.43 | 4.863 | 1.2 x 10-6 | 5.761 | 8.4 x 10-9 | GNPDA2 | * |
15 | rs12509595 | 4:81,182,554 | 81,158,545 | 81,202,048 | C | T | 0.31 | 2.318 | 2.1 x 10-2 | 6.651 | 2.9 x 10-11 | FGF5 | * |
16 | rs6841473 | 4:148,407,652 | 148,364,920 | 148,427,503 | T | C | 0.14 | 2.425 | 1.5 x 10-2 | 5.617 | 1.9 x 10-8 | EDNRA | * |
17 | rs55670004 | 5:127,909,723 | 127,801,058 | 128,014,538 | C | T | 0.31 | 2.988 | 2.6 x 10-3 | 5.908 | 3.5 x 10-9 | FBN2 | |
18 | rs2277923 | 5:172,662,024 | 172,509,305 | 172,677,800 | T | C | 0.70 | 3.552 | 3.7 x 10-4 | 6.853 | 7.2 x 10-12 | NKX2-5 | |
19 | rs62389955 | 6:12,902,248 | 12,795,031 | 12,948,388 | A | G | 0.67 | 0.893 | 3.7 x 10-1 | 6.838 | 8.0 x 10-12 | TBC1D7 | |
20 | rs12662582 | 6:18,383,060 | 18,235,776 | 18,401,608 | T | C | 0.29 | 2.128 | 3.3 x 10-2 | 5.684 | 1.3 x 10-8 | RNF144B | |
21 | rs7766436 | 6:22,598,259 | 22,556,885 | 22,620,904 | T | C | 0.28 | 4.651 | 3.8 x 10-6 | 7.262 | 3.8 x 10-13 | HDGFL1 | * |
22 | rs9343824 | 6:79,497,569 | 79,345,249 | 79,857,900 | G | A | 0.36 | 4.458 | 8.5 x 10-6 | 6.183 | 6.3 x 10-10 | IRAK1BP1 | * |
23 | rs242276 | 6:88,046,377 | 87,815,501 | 88,070,410 | A | G | 0.63 | 3.951 | 8.1 x 10-5 | 5.844 | 5.1 x 10-9 | SMIM8 | |
24 | rs11773845 | 7:116,191,301 | 116,003,990 | 116,206,665 | A | C | 0.59 | 2.873 | 4.2 x 10-3 | 7.996 | 1.3 x 10-15 | CAV1 | |
25 | rs56179563 | 7:129,685,597 | 129,663,496 | 129,685,597 | G | A | 0.62 | 3.289 | 1.0 x 10-3 | 6.539 | 6.2 x 10-11 | KLHDC10 | |
26 | rs2269997 | 7:139,723,400 | 139,717,178 | 139,761,248 | G | A | 0.79 | 3.708 | 2.1 x 10-4 | 5.480 | 4.3 x 10-8 | PARP12 | |
27 | rs3918226 | 7:150,690,176 | 150,690,176 | 150,690,176 | T | C | 0.08 | 4.028 | 6.0 x 10-5 | 6.799 | 1.1 x 10-11 | NOS3 | * |
28 | rs2954033 | 8:126,493,746 | 126,474,830 | 126,507,389 | A | G | 0.30 | 4.302 | 1.5 x 10-5 | 6.450 | 1.1 x 10-10 | TRIB1 | |
29 | rs446540 | 9:97,509,199 | 97,443,341 | 97,858,961 | A | G | 0.40 | 4.241 | 2.5 x 10-5 | 7.153 | 8.5 x 10-13 | AOPEP | * |
30 | rs2505083 | 10:30,335,122 | 30,300,787 | 30,335,520 | C | T | 0.42 | 0.888 | 3.8 x 10-1 | 5.540 | 3.0 x 10-8 | JCAD | |
31 | rs1332329 | 10:91,003,419 | 91,002,804 | 91,014,061 | C | A | 0.36 | 3.704 | 2.2 x 10-4 | 6.830 | 8.5 x 10-12 | LIPA | |
32 | rs7101148 | 10:105,481,879 | 105,324,774 | 105,548,935 | C | T | 0.25 | 3.211 | 1.4 x 10-3 | 6.854 | 7.2 x 10-12 | SH3PXD2A | |
33 | rs360153 | 11:9,762,274 | 9,750,757 | 9,779,277 | C | T | 0.59 | 3.363 | 7.2 x 10-4 | 5.672 | 1.4 x 10-8 | SWAP70 | |
34 | rs10507248 | 12:114,797,093 | 114,766,735 | 114,808,638 | T | G | 0.72 | 2.170 | 3.0 x 10-2 | 6.451 | 1.1 x 10-10 | TBX5 | |
35 | rs1169284 | 12:121,419,926 | 121,380,544 | 121,471,337 | C | T | 0.32 | 4.386 | 1.2 x 10-5 | 6.646 | 3.0 x 10-11 | OASL | |
36 | rs11057830 | 12:125,307,053 | 125,303,254 | 125,316,743 | A | G | 0.14 | 4.513 | 5.9 x 10-6 | 6.464 | 1.0 x 10-10 | SCARB1 | |
37 | rs1887200 | 13:111,393,137 | 111,351,369 | 111,406,396 | C | A | 0.21 | 2.895 | 4.0 x 10-3 | 5.669 | 1.4 x 10-8 | ING1 | |
38 | rs2145587 | 14:32,981,484 | 32,971,599 | 32,992,334 | A | G | 0.29 | 3.742 | 2.0 x 10-4 | 5.688 | 1.3 x 10-8 | AKAP6 | |
39 | rs7145262 | 14:100,125,721 | 100,110,120 | 100,184,101 | T | C | 0.43 | 2.850 | 4.4 x 10-3 | 5.850 | 4.9 x 10-9 | HHIPL1 | |
40 | rs72743461 | 15:67,441,750 | 67,441,750 | 67,468,285 | C | A | 0.76 | 2.391 | 1.7 x 10-2 | 6.468 | 9.9 x 10-11 | SMAD3 | |
41 | rs8039305 | 15:91,422,543 | 91,412,850 | 91,429,042 | C | T | 0.47 | 1.646 | 9.9 x 10-2 | 5.493 | 4.0 x 10-8 | FES | |
42 | rs67329386 | 16:73,048,367 | 73,005,822 | 73,076,819 | T | C | 0.18 | 2.495 | 1.2 x 10-2 | 8.898 | 5.7 x 10-19 | HP | * |
43 | rs6564260 | 16:75,447,426 | 75,304,497 | 75,516,739 | G | A | 0.58 | 3.788 | 1.7 x 10-4 | 5.743 | 9.3 x 10-9 | CFDP1 | |
44 | rs7500448 | 16:83,045,790 | 83,013,096 | 83,058,508 | A | G | 0.76 | 2.337 | 2.0 x 10-2 | 5.805 | 6.5 x 10-9 | CDH13 | |
45 | rs11651451 | 17:2,098,417 | 2,015,612 | 2,216,258 | T | C | 0.38 | 3.350 | 8.3 x 10-4 | 6.609 | 3.9 x 10-11 | SRR | * |
46 | rs17608766 | 17:45,013,271 | 44,967,530 | 45,244,074 | C | T | 0.14 | 3.708 | 2.2 x 10-4 | 6.467 | 1.0 x 10-10 | GOSR2 | * |
47 | rs7220955 | 17:76,700,063 | 76,661,269 | 76,833,916 | G | A | 0.45 | 4.113 | 3.6 x 10-5 | 6.175 | 6.6 x 10-10 | USP36 | * |
48 | rs1788826 | 18:21,154,024 | 21,074,255 | 21,165,163 | G | A | 0.36 | 4.321 | 1.7 x 10-5 | 5.680 | 1.3 x 10-8 | NPC1 | * |
49 | rs866245 | 18:46,527,026 | 46,474,192 | 46,528,787 | C | A | 0.68 | 3.107 | 1.9 x 10-3 | 6.286 | 3.3 x 10-10 | SMAD7 | |
50 | rs6511720 | 19:11,202,306 | 11,186,711 | 11,210,912 | G | T | 0.89 | 3.954 | 8.1 x 10-5 | 7.570 | 3.7 x 10-14 | LDLR | * |
51 | rs4315609 | 21:30,605,089 | 30,519,457 | 30,608,884 | G | A | 0.16 | 4.290 | 1.8 x 10-5 | 5.686 | 1.3 x 10-8 | MAP3K7CL | |
52 | rs28451064 | 21:35,593,827 | 35,593,827 | 35,680,301 | A | G | 0.13 | 2.542 | 1.1 x 10-2 | 7.944 | 2.0 x 10-15 | MRPS6 | * |
L1 | rs17035646 | 1:10,796,547 | 10,789,634 | 10,802,468 | A | G | 0.40 | 5.288 | 1.6 x 10-7 | 7.139 | 9.4 x 10-13 | CASZ1 | * |
L3 | rs11591147 | 1:55,505,647 | 55,487,648 | 55,505,647 | G | T | 0.98 | 2.721 | 6.5 x 10-3 | 6.927 | 4.3 x 10-12 | PCSK9 | |
L6 | rs1230666 | 1:114,173,410 | 114,173,410 | 114,173,410 | A | G | 0.15 | 3.039 | 2.3 x 10-3 | 5.785 | 7.3 x 10-9 | DCLRE1B | |
L11 | rs16986953 | 2:19,942,473 | 19,942,473 | 19,942,473 | A | G | 0.18 | 3.610 | 3.3 x 10-4 | 6.695 | 2.2 x 10-11 | TTC32 | |
L12 | rs4076834 | 2:44,081,627 | 44,052,743 | 44,097,367 | T | G | 0.92 | 5.286 | 1.2 x 10-7 | 6.721 | 1.8 x 10-11 | ABCG5 | |
L15 | rs12992231 | 2:148,799,710 | 148,543,968 | 148,915,190 | A | C | 0.39 | 4.176 | 3.3 x 10-5 | 5.562 | 2.7 x 10-8 | ORC4 | |
L18 | rs3819325 | 3:49,843,723 | 49,734,229 | 49,890,613 | C | T | 0.48 | 5.091 | 3.9 x 10-7 | 6.275 | 3.5 x 10-10 | UBA7 | |
L20 | rs34894639 | 3:135,798,658 | 135,798,658 | 136,468,503 | C | T | 0.78 | 4.016 | 6.4 x 10-5 | 7.067 | 1.6 x 10-12 | PCCB | |
L21 | rs1713804 | 3:153,799,122 | 153,622,907 | 153,946,463 | G | A | 0.85 | 4.165 | 2.9 x 10-5 | 6.083 | 1.2 x 10-9 | DHX36 | |
L22 | rs11545169 | 3:184,020,542 | 183,976,103 | 184,044,433 | G | T | 0.84 | 4.905 | 8.3 x 10-7 | 5.536 | 3.1 x 10-8 | PSMD2 | |
L23 | rs11730486 | 4:77,418,968 | 77,364,799 | 77,437,749 | G | A | 0.39 | 3.529 | 4.6 x 10-4 | 5.993 | 2.1 x 10-9 | SHROOM3 | |
L26 | rs11731886 | 4:156,659,819 | 156,613,960 | 156,677,592 | A | C | 0.77 | 3.483 | 4.7 x 10-4 | 6.731 | 1.7 x 10-11 | GUCY1A1 | |
L27 | rs869396 | 4:169,688,000 | 169,682,578 | 169,708,457 | C | A | 0.52 | 3.900 | 1.1 x 10-4 | 6.200 | 5.6 x 10-10 | CBR4 | |
L28 | rs17263917 | 5:9,552,338 | 9,538,296 | 9,557,120 | G | A | 0.85 | 2.273 | 2.3 x 10-2 | 5.621 | 1.9 x 10-8 | SEMA5A | |
L29 | rs13179413 | 5:55,868,097 | 55,854,153 | 55,868,097 | T | C | 0.26 | 4.322 | 1.4 x 10-5 | 6.029 | 1.7 x 10-9 | MAP3K1 | |
L30 | rs1309540 | 5:64,293,570 | 64,239,880 | 64,326,696 | A | G | 0.14 | 3.958 | 7.3 x 10-5 | 5.467 | 4.6 x 10-8 | CWC27 | |
L31 | rs159403 | 5:106,218,743 | 106,217,453 | 106,265,125 | A | G | 0.62 | 4.615 | 3.9 x 10-6 | 5.900 | 3.6 x 10-9 | NA | |
L33 | rs3776307 | 5:142,494,165 | 142,494,165 | 142,507,651 | G | A | 0.45 | 2.434 | 1.6 x 10-2 | 5.713 | 1.1 x 10-8 | ARHGAP26 | |
L35 | rs12519997 | 5:173,351,858 | 173,269,956 | 173,394,975 | G | A | 0.45 | 5.098 | 3.4 x 10-7 | 6.081 | 1.2 x 10-9 | CPEB4 | |
L36 | rs9501744 | 6:1,617,143 | 1,616,265 | 1,626,055 | C | T | 0.86 | 3.300 | 1.1 x 10-3 | 5.519 | 3.4 x 10-8 | GMDS |
L38 | rs41269297 | 6:28,297,368 | 28,230,796 | 28,597,364 | A | G | 0.05 | 4.517 | 6.2 x 10-6 | 5.474 | 4.4 x 10-8 | ZSCAN31 | |
L39 | rs2814948 | 6:34,653,413 | 34,548,206 | 34,898,744 | A | G | 0.17 | 5.278 | 1.5 x 10-7 | 6.683 | 2.3 x 10-11 | ILRUN | |
L40 | rs3798519 | 6:50,788,778 | 50,787,459 | 50,940,677 | C | A | 0.21 | 4.581 | 4.5 x 10-6 | 5.574 | 2.5 x 10-8 | TFAP2B | |
L41 | rs12191844 | 6:57,109,452 | 57,107,322 | 57,160,572 | C | T | 0.52 | 3.255 | 1.2 x 10-3 | 5.537 | 3.1 x 10-8 | RAB23 | |
L42 | rs12193973 | 6:134,151,297 | 134,150,561 | 134,209,837 | C | T | 0.69 | 2.545 | 1.1 x 10-2 | 6.034 | 1.6 x 10-9 | TCF21 | |
L43 | rs140300817 | 6:159,880,605 | 159,880,605 | 159,880,605 | C | T | 0.02 | 3.484 | 4.8 x 10-4 | 5.561 | 2.7 x 10-8 | WTAP | |
L44 | rs57234495 | 7:1,906,466 | 1,860,733 | 2,021,248 | G | A | 0.80 | 3.635 | 2.5 x 10-4 | 5.491 | 4.0 x 10-8 | MAD1L1 | |
L45 | rs3828944 | 7:6,487,156 | 6,412,113 | 6,488,097 | C | T | 0.78 | 4.369 | 1.2 x 10-5 | 5.771 | 7.9 x 10-9 | DAGLB | |
L49 | rs2119690 | 8:19,859,539 | 19,763,992 | 19,934,339 | G | A | 0.71 | 4.390 | 9.7 x 10-6 | 7.217 | 5.3 x 10-13 | LPL | |
L51 | rs11257613 | 10:12,284,392 | 12,242,095 | 12,308,889 | G | A | 0.51 | 4.040 | 5.7 x 10-5 | 5.592 | 2.2 x 10-8 | NUDT5 | |
L53 | rs1870634 | 10:44,480,811 | 44,478,975 | 44,691,633 | G | T | 0.67 | 1.717 | 9.0 x 10-2 | 5.558 | 2.7 x 10-8 | ZNF32 | |
L54 | rs7098414 | 10:82,214,586 | 82,162,509 | 82,230,146 | A | C | 0.26 | 4.689 | 2.9 x 10-6 | 5.869 | 4.4 x 10-9 | TSPAN14 | |
L56 | rs4604804 | 10:99,878,997 | 99,863,549 | 100,026,791 | G | A | 0.58 | 4.451 | 7.4 x 10-6 | 6.272 | 3.6 x 10-10 | R3HCC1L | |
L59 | rs604723 | 11:100,610,546 | 100,511,849 | 100,692,566 | C | T | 0.69 | 3.161 | 1.6 x 10-3 | 5.797 | 6.8 x 10-9 | ARHGAP42 | |
L60 | rs1384705 | 11:103,696,851 | 103,660,567 | 103,696,851 | C | T | 0.34 | 0.309 | 7.6 x 10-1 | 5.564 | 2.6 x 10-8 | DDI1 | |
L61 | rs7938944 | 11:118,954,066 | 118,917,814 | 118,958,869 | C | T | 0.37 | 4.264 | 2.2 x 10-5 | 6.211 | 5.3 x 10-10 | HMBS | |
L62 | rs12578168 | 12:95,511,321 | 95,499,888 | 95,522,289 | G | A | 0.80 | 2.813 | 4.9 x 10-3 | 5.631 | 1.8 x 10-8 | FGD6 | |
L64 | rs4765127 | 12:124,460,167 | 124,401,710 | 124,496,316 | G | T | 0.69 | 2.473 | 1.4 x 10-2 | 5.630 | 1.8 x 10-8 | CCDC92 | |
L66 | rs9515203 | 13:111,049,623 | 110,918,660 | 111,049,623 | T | C | 0.75 | 4.881 | 9.2 x 10-7 | 7.978 | 1.5 x 10-15 | COL4A2 | |
L69 | rs7173743 | 15:79,141,784 | 79,071,095 | 79,157,405 | T | C | 0.57 | 1.196 | 2.3 x 10-1 | 7.249 | 4.2 x 10-13 | ADAMTS7 | |
L70 | rs2062316 | 15:81,010,249 | 80,987,012 | 81,060,753 | G | A | 0.41 | 4.833 | 1.1 x 10-6 | 5.854 | 4.8 x 10-9 | ABHD17C | |
L71 | rs1879454 | 15:81,377,717 | 81,349,147 | 81,398,791 | C | A | 0.24 | 3.571 | 3.5 x 10-4 | 5.795 | 6.8 x 10-9 | CFAP161 | |
L73 | rs9284324 | 16:15,902,715 | 15,901,778 | 15,919,352 | G | A | 0.67 | 3.855 | 1.1 x 10-4 | 6.215 | 5.1 x 10-10 | MYH11 | |
L74 | rs17231506 | 16:56,994,528 | 56,987,015 | 57,001,274 | C | T | 0.71 | 3.509 | 4.8 x 10-4 | 5.700 | 1.2 x 10-8 | NLRC5 | |
L76 | rs62043959 | 16:81,525,204 | 81,491,181 | 81,551,482 | A | C | 0.75 | 4.131 | 3.1 x 10-5 | 5.531 | 3.2 x 10-8 | CMIP | |
L78 | rs3794730 | 17:28,150,359 | 27,935,546 | 28,413,129 | G | A | 0.33 | 3.839 | 1.1 x 10-4 | 5.718 | 1.1 x 10-8 | CORO6 | |
L80 | rs11655587 | 17:47,140,794 | 46,917,953 | 47,207,658 | C | T | 0.67 | 5.037 | 4.4 x 10-7 | 6.702 | 2.0 x 10-11 | ATP5MC1 | |
L81 | rs4968535 | 17:59,245,274 | 58,908,505 | 59,312,048 | T | C | 0.22 | 3.590 | 3.4 x 10-4 | 5.701 | 1.2 x 10-8 | BCAS3 | |
L84 | rs78030362 | 19:18,575,193 | 18,575,193 | 18,589,943 | G | A | 0.08 | 3.057 | 2.2 x 10-3 | 6.408 | 1.5 x 10-10 | LRRC25 | |
L85 | rs2241712 | 19:41,869,756 | 41,757,707 | 41,945,904 | C | T | 0.34 | 3.691 | 2.2 x 10-4 | 6.502 | 7.9 x 10-11 | BCKDHA | * |
L86 | rs7412 | 19:45,412,079 | 45,400,747 | 45,426,792 | C | T | 0.93 | -0.461 | 6.5 x 10-1 | 6.937 | 4.0 x 10-12 | APOE | |
L89 | rs58099562 | 22:42,453,772 | 42,441,091 | 42,628,335 | T | C | 0.81 | 4.551 | 5.6 x 10-6 | 5.468 | 4.5 x 10-8 | CYP2D6 |
