Table 1 Top significantly differentially expressed genes for each comparison group

From: The effects of space radiation on the transcriptome of heart right ventricle tissue

Gene type

Gene name

Description

log2FoldChange

padj

Male, γ-IR

protein_coding

Iigp1

interferon inducible GTPase 1

1.362

0.04

protein_coding

Mapt

microtubule-associated protein tau

1.278

0.003

Male, simGCRsim-IR

protein_coding

Myh7

myosin, heavy polypeptide 7, cardiac muscle, beta

1.235

0.05

protein_coding

Myot

Myotilin

1.192

0.007

lncRNA

Gm29015

predicted gene 29015

1.135

0.03

protein_coding

Ifitm1

Interferon-induced transmembrane protein 1

1.09

0.000001

protein_coding

Gm50092

predicted gene, 50092

0.969

0.02

protein_coding

Ddit4

DNA-damage-inducible transcript 4

0.908

0.04

protein_coding

Sf3a2

splicing factor 3a, subunit 2

0.868

0.01

processed_pseudogene

Ldhb-ps

lactate dehydrogenase B, pseudogene

0.837

0.03

protein_coding

Cox5a

cytochrome c oxidase subunit 5A

0.812

0.04

lncRNA

Gm57414

predicted gene, 57414

0.763

0.02

protein_coding

Myl4

myosin, light polypeptide 4

−4.522

0.001

protein_coding

Nppb

natriuretic peptide type B

−2.042

0.03

protein_coding

Stard10

START domain containing 10

−2.022

0.0003

protein_coding

Cytl1

cytokine-like 1

−1.92

0.003

protein_coding

Gpx3

glutathione peroxidase 3

−1.707

0.0009

protein_coding

Pam

peptidylglycine alpha-amidating monooxygenase

−1.505

0.02

protein_coding

Myl9

myosin, light polypeptide 9, regulatory

−1.486

0.003

protein_coding

Dpysl3

dihydropyrimidinase-like 3

−1.252

0.0005

protein_coding

Scrn1

secernin 1

−1.232

0.001

protein_coding

Ccn2

cellular communication network factor 2

−1.215

0.05

Female, simGCRsim-IR

protein_coding

Kansl1

KAT8 regulatory NSL complex subunit 1

0.508

0.04

protein_coding

Ier3

immediate early response 3

−0.533

0.04

  1. For the male simGCRsim-IR group, only the top 10 up- and down-regulated genes are presented.