Table 2 Comparison of behavioral and objective gait outcome measures

From: Effect of cerebrospinal dual-site magnetic stimulation on freezing of gait in Parkinson’s disease

Outcomes

Group

Baseline

Post

Post1m

Primary outcome measure

FOG-Q

DS

17.11 ± 4.15

13.05 ± 4.03***

13.74 ± 4.03***

SS

16.33 ± 4.61

14.11 ± 3.66***

14.94 ± 4.08**

NS

17.78 ± 4.10

18.22 ± 4.12

18.67 ± 4.06

Secondary outcome measures

UPDRS-III

DS

28.47 ± 11.82

22.63 ± 9.56***

22.79 ± 9.07***

SS

32.94 ± 8.03

27.0 ± 7.33***

27.56 ± 7.45***

NS

29.44 ± 11.41

29.61 ± 11.88

30.94 ± 12.11

Gait speed, m/s

DS

0.55 ± 0.19

0.71 ± 0.18***

0.70 ± 0.19***

SS

0.58 ± 0.25

0.67 ± 0.26**

0.62 ± 0.25

NS

0.51 ± 0.27

0.45 ± 0.21

0.42 ± 0.27*

Stride length, cm

DS

58.28 ± 19.34

75.01 ± 19.07***

72.62 ± 18.64***

SS

64.50 ± 26.72

71.54 ± 27.90

66.58 ± 28.48

NS

56.25 ± 28.45

48.48 ± 21.17*

45.25 ± 27.98**

Stride time variability, %

DS

8.10 ± 5.44

6.14 ± 5.39

5.96 ± 5.20

SS

7.42 ± 5.66

8.35 ± 5.95

8.42 ± 5.30

NS

9.74 ± 5.53

10.85 ± 5.57

12.51 ± 10.43

Double support time percentage, %

DS

26.76 ± 8.29

22.31 ± 6.21**

22.66 ± 5.89

SS

29.88 ± 9.53

25.99 ± 7.98*

27.79 ± 7.44

NS

31.73 ± 12.54

31.83 ± 9.50

36.56 ± 12.57**

  1. Values were presented as mean ± SD.
  2. DS dual-site, NS no-site, FOG-Q freezing of gait questionnaire; Post 1 day postintervention; Post1m 1 month postintervention, SS single-site, UPDRS-III Unified Parkinson’s Disease Rating Scale part III.
  3. *p < 0.05 when compared to Baseline. **p < 0.01 when compared to Baseline. ***p < 0.001 when compared to Baseline. These p-values were corrected by Bonferroni.