Table 2 Frequency of the LRRK2 p.L1795F and p.G2019S variants across ancestries in the GP2 genotyping cohort
From: The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population
Variant | Ancestry | AF in cases (allele count) | AF in controls (allele count) | Number of alleles in cases | Number of alleles in controls |
|---|---|---|---|---|---|
chr12:40322386:G:T (LRRK2 p.L1795F) | EUR | 0.0001201 (5) | 0 (0) | 41634 | 18064 |
chr12:40340400:G:A (LRRK2 p.G2019S) | AAC | 0 (0) | 0.0006281 (1) | 568 | 1592 |
AFR | 0 (0) | 0 (0) | 1876 | 3252 | |
AJ | 0.07081 (181) | 0.01098 (9) | 2556 | 820 | |
AMR | 0.01339 (12) | 0.003247 (1) | 896 | 308 | |
CAH | 0.006783 (7) | 0.003436 (2) | 1032 | 582 | |
CAS | 0 (0) | 0 (0) | 1104 | 688 | |
EAS | 0 (0) | 0 (0) | 5122 | 4752 | |
EUR | 0.003266 (136) | 0.000166 (3) | 41636 | 18074 | |
FIN | 0 (0) | 0 (0) | 192 | 14 | |
MDE | 0.02805 (17) | 0 (0) | 606 | 446 | |
SAS | 0 (0) | 0 (0) | 732 | 412 |
