Fig. 7: Cellular population analysis and cuproptosis in PD and melanoma. | npj Parkinson's Disease

Fig. 7: Cellular population analysis and cuproptosis in PD and melanoma.

From: Linking Parkinson’s disease and melanoma: the impact of copper-driven cuproptosis and related mechanisms

Fig. 7

A xCell analysis showing a significant reduction in neuronal populations in PD tissues. B, C xCell analysis indicating decreased neuronal and melanocyte populations in melanoma tissues. D Association of hub genes with neuronal populations in PD. E Association of hub genes with melanocyte populations in melanoma. F Elevated cuproptosis levels in PD neurons. G Elevated cuproptosis levels in melanoma melanocytes. H Sankey diagram illustrating the relationships between hub genes and cuproptosis in PD neurons. I Sankey diagram illustrating the relationships between hub genes and cuproptosis in melanoma melanocytes.

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