Fig. 3: Analysis of calorie intake.

Average daily calorie intake was measured weekly. Although the differences in the levels of calorie intake between α-Syn and control mice in the high-fat and regular diet groups were only modest, they were significant (P < 0.0001; Time × Genotype for each diet; b–d), except for that of the 1-month male (a) regular diet sub-group (P = 0.3351). The number of mice for each group is shown in parentheses. Statistical analysis was performed separately for the high-fat diet and regular diet groups in a–d, using two-way repeated measures ANOVA.