Fig. 3: Annual mean or prevalence of MetS components in PD patients and control subjects stratified by sex in the years before the DoD.

The results are calculated based on data collected in the previous year until the DoD (red dashed vertical line); for example, “-3” relates to the mean blood test value calculated during the fourth year (from year 3 to year 4) before the DoD. For controls, the DoD is defined by the DoD of their matched patient with PD (see the Methods section). Numbers of subjects are averaged over 10 datasets of patients and controls with available values. a Mean TG values. b Mean HDL values. c Mean LDL/HDL values. d Mean BMI values. e Prevalence of pharmacologic treatment for hypertension. f Prevalence of pharmacologic treatment for type 2 diabetes.