Fig. 3: Comparison of plasma αSyn aggregate levels using CSIC between groups.
From: A novel approach to detecting plasma synuclein aggregates for Parkinson’s disease diagnosis
a Box and whisker plots showing the range and average distribution of αSyn aggregates detected using CSIC. Statistical analysis was conducted using Mann-Whitney U tests due to the non-parametric distribution, with significant differences between the HC and PD groups at p < 0.0001 (****) indicated. b ROC curve of αSyn aggregates in accordance with CSIC parameters for discriminating patients with PD from HC. c Repeatability and reproducibility tests. Repeatability assays were conducted on plasma samples from healthy individuals (n = 3) and patients with PD (n = 3). Each sample was tested three times by three different experimenters to assess the reproducibility of the assay.
