Table 1 Demographic and clinical features of the cohort
From: Phosphorylated α-synuclein in CSF and plasma does not reflect synucleinopathy
PD/PDD | AD | CTRL | ||||||
|---|---|---|---|---|---|---|---|---|
PD-CN | PD-MCI | PDD | pre-AD | MCI-AD | AD-dem | CTRL-CN | CTRL-MCI | |
N | 16 | 26 | 5 | 19 | 30 | 31 | 21 | 21 |
Sex (% M) | 56 | 77 | 100 | 26 | 27 | 29 | 67 | 33 |
Age (y) | 64.6 ± 6.2 | 67.7 ± 6 | 75.8 ± 3.3 | 72.8 ± 5.9 | 71.4 ± 5.7 | 71.4 ± 7.5 | 66.2 ± 6.4 | 72.8 ± 6.9 |
MMSE T0 | 28.6 ± 1.4 | 25.8 ± 2.1 | 21.4 ± 3.2 | 27.9 ± 1.1 | 22.9 ± 3.3 | 16.5 ± 6.2 | 28.5 ± 1 | 25.2 ± 2.6 |
CDR T0 | – | – | – | 0 ± 0 | 0.5 ± 0 | 1.2 ± 0.4 | – | – |
MoCA T0 | 25.9 ± 2.6 | 19.3 ± 4.1 | 14.4 ± 1.1 | – | – | – | – | – |
UPDRS-III T0 | 27 ± 7.7 | 31.8 ± 9.8 | 33.5 ± 17.3 | – | – | – | – | – |
H&Y T0 | 2.1 ± 0.6 | 2.3 ± 0.4 | 2.6 ± 1.2 | – | – | – | – | – |
A + (%) | 0 | 15 | 80 | 100 | 100 | 100 | 0 | 14 |
T + (%) | 19 | 15 | 60 | 100 | 100 | 100 | 33 | 14 |
N + (%) | 6 | 15 | 20 | 58 | 97 | 97 | 19 | 5 |
A + T + (%) | 0 | 8 | 60 | 100 | 100 | 100 | 0 | 0 |
S + (%) | 88 | 85 | 80 | 26 | 30 | 39 | 0 | 0 |
