Table 1 Baseline Characteristics of Parkinson’s disease

From: Associations of digestive diseases exposure and lifestyle factors with Parkinson’s disease

Characteristic

Overall

Without Parkinson’s disease

Parkinson’s disease

P value

(n = 501483)

(n = 498577)

(n = 2906)

 

Age at baseline, years (mean (SD))

 

56.52 (8.10)

56.48 (8.09)

63.12 (5.23)

<0.001

Sex, n (%)

Female

2,72,967 (54.43)

2,71,887 (54.53)

1080 (37.16)

<0.001

Male

2,28,516 (45.57)

2,26,690 (45.47)

1826 (62.84)

 

TDI (mean (SD))

 

−1.29 (3.09)

−1.29 (3.09)

−1.35 (3.08)

0.346

BMI, kg/m2 (mean (SD))

 

27.43 (4.79)

27.43 (4.79)

27.80 (4.57)

<0.001

Educational attainment, n (%)

College or University degree

1,62,989 (32.50)

1,62,193 (32.53)

796 (27.39)

<0.001

Vocational

26,862 (5.36)

26,776 (5.37)

86 (2.96)

 

Any school degree

55,220 (11.01)

54,963 (11.02)

257 (8.84)

 

Other

2,56,412 (51.13)

2,54,645 (51.07)

1767 (60.81)

 

Health diet (mean (SD))

 

3.05 (1.24)

3.05 (1.24)

3.09 (1.22)

0.113

Smoking status, n (%)

Never

2,75,098 (54.86)

2,73,603 (54.88)

1495 (51.45)

<0.001

Previous

1,73,477 (34.59)

1,72,265 (34.55)

1212 (41.71)

 

Current

52,908 (10.55)

52,709 (10.57)

199 (6.85)

 

Alcohol consumption, n (%)

Never

22,324 (4.45)

22,159 (4.44)

165 (5.68)

<0.001

Previous

18,015 (3.59)

17,846 (3.58)

169 (5.82)

 

Current

4,61,144 (91.96)

4,58,572 (91.98)

2572 (88.51)

 

Physical activity (mean (SD))

 

2660.67 (2447.14)

2661.32 (2447.92)

2548.01 (2306.41)

0.013

Ethnicity, n (%)

White

4,58,139 (91.36)

4,55,399 (91.34)

2740 (94.29)

<0.001

Asia

9412 (1.88)

9374 (1.88)

38 (1.31)

 

Black

3418 (0.68)

3407 (0.68)

11 (0.38)

 

Other

30,514 (6.08)

30,397 (6.10)

117 (4.03)

 

Hypertension, n (%)

Normal

74,930 (14.94)

74,654 (14.97)

276 (9.50)

<0.001

Elevated

53,981 (10.76)

53,715 (10.77)

266 (9.15)

 

Stage 1 hypertension

1,23,834 (24.69)

1,23,204 (24.71)

630 (21.68)

 

Stage 2 hypertension

2,48,738 (49.60)

2,47,004 (49.54)

1734 (59.67)

 

Family history of PD, n (%)

No

4,99,229 (99.55)

4,96,353 (99.55)

2876 (98.97)

<0.001

Yes

2254 (0.45)

2224 (0.45)

30 (1.03)

 
  1. Continuous variables are expressed in mean (SD), and categorical variables are in number (%).
  2. TDI Townsend deprivation index.