Table 1 Demographic and clinical data of the different subtype of PD patients and HC

From: Synthetic MRI study of brain volume and subcortical myelin in various Parkinson’s disease motor subtypes

 

level

HC (n = 39)

TD (n = 39)

PIGD (n = 53)

F/t/χ2

P values

Age (years)

 

63.026 ± 5.183

63.41 ± 9.931

66.151 ± 8.958

1.964

0.145

Education (years)

 

7.385 ± 2.267

7.846 ± 2.72

8.34 ± 3.818

1.074

0.345

Gender (%)

Man

22 (56.41)

22 (56.41)

26 (49.06)

0.487

0.485

Female

17 (43.59)

17 (43.59)

27 (50.94)

  

MHY (%)

Early

 

31 (79.49)

22 (41.51)

13.269

<0.001*

 

Advanced

 

8 (20.51)

31 (58.49)

  

Symptom-dominant side

Left

 

16

35

4.7221

0.030

 

Right

 

23

18

  

Durition (years)

  

4.021 ± 4.631

5.264 ± 3.65

−1.440

0.153

MDS-UPDRS_I score

  

12.692 ± 6.075

15.604 ± 5.454

−2.411

0.018*

MDS-UPDRS_II score

  

15.256 ± 7.347

18.509 ± 7.433

−2.084

0.04*

MDS-UPDRS_III score

  

28.897 ± 14.349

39.604 ± 15.146

−3.426

<0.001*

  1. PD Parkinson’s Disease, HCs health controls, TD tremor-dominant subtype, PIGD postural instability and gait difficulty subtypem, MDS-UPDRS Movement Disorder Society-Unified Parkinson’s Disease Rating Scale, MHY modified Hoehn and Yahr scale.
  2. Early-stage: modify H-Y grade 1–2.5, Advanced-stage: modify H-Y grade 3–5.
  3. *p < 0.05.