Table 2 Concentration of amino acids in the groups investigated.
From: Variations of blood D-serine and D-aspartate homeostasis track psychosis stages
AA | HC | ARMS | FEP | SCZ | p-value |
|---|---|---|---|---|---|
L-Ser, µM | 120 (103–139) | 132 (114–152) | 118 (105–138) | 147 (130–175) | <0.001 |
D-Ser, µM | 1.44 (1.10–1.83) | 1.89 (1.53–2.17) | 1.67 (1.32–2.00) | 1.39 (1.14–1.63) | <0.001 |
D-Ser/Total, % | 1.15 (0.96–1.39) | 1.37 (1.04–1.76) | 1.25 (1.09–1.53) | 0.87 (0.74–1.09) | <0.001 |
L-Asp, µM | 14.6 (10.8–19.2) | 11.7 (7.1–20.8) | 15.4 (10.4–24.6) | 24.3 (17.5–32.1) | <0.001 |
D-Asp, µM | 0.18 (0.08–0.33) | 0.29 (0.19–0.43) | 0.33 (0.28–0.69) | 0.20 (0.10–0.39) | <0.001 |
D-Asp/Total, % | 1.23 (0.44–2.20) | 2.43 (1.67–3.23) | 2.56 (1.84–3.32) | 0.78 (0.40–1.76) | <0.001 |
L-Gln, µM | 355 (314–393) | 357 (310–398) | 317 (293–357) | 350 (312–394) | 0.263 |
L-Glu, µM | 28.1 (15.1–44.1) | 22.7 (13.2–32.2) | 30.4 (22.9–43.0) | 88.0 (42.3–132.2) | <0.001 |
L-Gln/L-Glu | 13.4 (8.7–22.2) | 16.0 (11.4–26.2) | 11.3 (7.2–17.3) | 4.2 (2.6–7.7) | <0.001 |
L-Asn, µM | 40.5 (34.1–47.1) | 40.8 (34.3–48.1) | 39.6 (31.9–48.1) | 43.5 (36.7–53.4) | 0.126 |
Gly, µM | 201 (171–236) | 209 (179–256) | 195 (152–244) | 257 (210–310) | <0.001 |
