Fig. 2: Fractional isotropy (FA) difference maps overlaid on white matter (WM) tract skeletons illustrating regional changes in WM integrity among patients with schizophrenia and medication-resistant AVHs. | Schizophrenia

Fig. 2: Fractional isotropy (FA) difference maps overlaid on white matter (WM) tract skeletons illustrating regional changes in WM integrity among patients with schizophrenia and medication-resistant AVHs.

From: Common and unique white matter fractional anisotropy patterns in patients with schizophrenia with medication-resistant auditory verbal hallucinations: a retrospective tract-based spatial statistics study

Fig. 2

Images show FA changes as pseudocolors in the parasagittal plane (left panels), coronal plane (middle panels), and transverse plane (right panels). A Patients with medication-resistant AVHs demonstrated significantly greater FA in the corpus callosum fasciculus at baseline compared to healthy controls. B Patients with medication-resistant AVHs demonstrated significantly greater FA in the corticospinal tract (but not the corpus callosum fasciculus) after 5 years of antipsychotic drug treatment compared to healthy controls. C Patients with medication-resistant AVHs demonstrated significantly greater FA in the superior longitudinal fasciculus post-treatment compared to baseline.

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