Fig. 2: Identification of core targets of valbenazine and deutetrabenazine through protein-protein interaction network analysis. | Schizophrenia

Fig. 2: Identification of core targets of valbenazine and deutetrabenazine through protein-protein interaction network analysis.

From: Unique and overlapping mechanisms of valbenazine, deutetrabenazine, and vitamin E for tardive dyskinesia

Fig. 2

A, E Venn diagrams indicating the common drug-disease targets. A valbenazine and TD; (E) deutetrabenazine and TD. B, F PPI network diagrams for the common targets obtained from the STRING database. B valbenazine; (F) deutetrabenazine. C, G PPI network maps generated using Cytoscape. C valbenazine; G deutetrabenazine. Redder coloration and larger size indicate a higher degree value in the PPI network. D, H Top 10 hub targets selected from the PPI network using the CytoHubba plugin, as ranked using the MCC method. D valbenazine; (H) deutetrabenazine.

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