Table 1 Comparisons of demographic, social function and neuroimaging characteristics between patients and HC groups.

From: Left amygdala alterations mediate the effects of negative symptoms on social dysfunction in schizophrenia

 

DS (N = 53)

NDS (N = 76)

HC(N = 76)

F/t

P

Age

50.60 ± 9.122

50.67 ± 7.762

50.46 ± 5.473

0.016

0.984

Education level (year)

8.64 ± 2.489

9.12 ± 2.678

9.45 ± 2.826

1.404

0.248

BMI

24.03 ± 3.30

24.83 ± 3.21

24.19 ± 2.29

1.432

0.241

SSPI

18.64 ± 7.930

31.97 ± 6.851

 

−9.926

<0.001

Life skill ability

7.75 ± 2.766

10.67 ± 1.595

 

−7.57

<0.001

Motility and social competence

6.57 ± 3.472

12.78 ± 3.281

 

−10.222

<0.001

Social activity skills

4.32 ± 3.024

8.66 ± 3.373

 

−7.641

<0.001

GMV of AMYG.L

1351 ± 162*, #

1441 ± 174*

1590 ± 225

25.779*

<0.001

GMV of AMYG.R

1572 ± 176*

1615 ± 203*

1792 ± 200

24.283

<0.001

  1. Data was presented as Mean ± SD.
  2. DS deficit schizophrenia, NDS non-deficit schizophrenia, HC healthy controls, BMI Body mass index, SSPI Scale of Social function in Psychosis Inpatients, GMV grey matter volume, AMYG.L the left amygdala, AMYG.R the right amygdala.
  3. * indicates the comparison between patients and HC. *p < 0.001. # indicates the comparison between DS and NDS. #p < 0.05.