Fig. 3: Results of colocalization analyses with PP.H4 > 80%.
From: Association between antidiabetic drug targets and psychiatric disorders
A The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between GANC expression in the putamen basal ganglia and BD risk, with other SNPs colored according to their LD r² with the lead SNP. B The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between GANC expression in the nucleus accumbens basal ganglia and BD risk, with other SNPs colored according to their LD r² with the lead SNP. C The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between GANC expression in the cortex and BD risk, with other SNPs colored according to their LD r² with the lead SNP. D The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between ABCC8 expression in the cortex and SCZ risk, with other SNPs colored according to their LD r² with the lead SNP. E The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between ABCC8 expression in the cerebellum and SCZ risk, with other SNPs colored according to their LD r² with the lead SNP. F The plot displays the lead SNP, which has the highest posterior probability for H4 in the colocalization analysis between ABCC8 expression in the cerebellar hemisphere and SCZ risk, with other SNPs colored according to their LD r² with the lead SNP. GWAS genome-wide association study, BD bipolar disorder, eQTL expression quantitative trait loci, GANC glucosidase alpha neutral C, SCZ schizophrenia, ABCC8 ATP-binding cassette subfamily C member 8, PP.H4 posterior probability for hypothesis 4.
