Fig. 7: Effect of RPP1 on colonic transcriptome profiles and key pathways.

a, b Volcano plot of gene expression in the colon of a group M mice compared to group C mice and b group PL mice compared to group M mice. c PCA plot of the transcriptome of mouse colon tissue. d Heat map of differential gene expression. e, f KEGG enrichment pathway of DEGs between e groups M and C and f groups PL and M. g KEGG enrichment pathway of common DEGs between groups M and C and groups PL and M. h KEGG enrichment pathway of common DEGs.