Fig. 7: The potential mechanism of Pls on the development of AS. | npj Science of Food

Fig. 7: The potential mechanism of Pls on the development of AS.

From: Effects of Mytilus edulis derived plasmalogens against atherosclerosis via lipid metabolism and MAPK signaling pathway

Fig. 7

HFD has a significant pro-atherogenic effect, which might be associated with provocation of AP-1 mediated inflammatory response mediated by calmodulin. In contrast, Pls supplementation effectively inhibits HFD-induced activation of MAPK signaling pathway, thereby preventing and the downstream inflammatory damage and blocking the development of HFD-related disorders, including atherosclerosis.

Back to article page