Table 2 IC50 values of purified compounds for inhibiting PMA-induced MUC5AC mRNA expression in NCI-H292 cells

From: Inhibitory effects of Raphanus sativus root extracts on MUC5AC gene expression in human airway epithelial cells

Concentration

(μM)

aDDMP + PMA

b5-HMF + PMA

c2-FPP + PMA

dMFPB + PMA

IC50 value

21.81

12.89

18.84

11.96

  1. aDDMP, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one.
  2. b5-HMF, 5-(Hydroxymethyl)furfural.
  3. c2-FPP, 2-(2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl) propanoic acid.
  4. dMFPB, 4-[formyl-5-(methoxymethyl)-1H-pyrrol-1-yl] butanoic acid.
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