Table 1 Characteristics of study subjects

From: Placental and cord blood DNA methylation in preterm birth: exploring the epigenetic role of maternal dietary protein

Maternal and neonatal characteristics

Term Birth

(Controls, n = 30)

Preterm Birth

(PTB, n = 18)

p-values

Age at enrollment in years (median (IQR))

24 (6.5)

21.5 (5)

0.2948

Weight at enrollment in kg (median (IQR))

48 (13.5)

48 (8.5)

0.3704

Height at enrollment in cm (median (IQR))

151.2 (5.3)

154.15 (6.17)

0.0691

Body mass index (BMI) in kg/m² (median (IQR))

21.49 (4.23)

20.12 (3.39)

0.1169

Negative HIV test (n (%))

30 (100)

18 (100)

 

Maternal Ethnic background (n (%)):

  

0.1018

 Burmese

8 (26.67)

9 (50)

0.2669

 Karen

22 (73.33)

9 (50)

0.4384

Gravida (n (%)):

 1

11 (36.67)

8 (44.44)

0.5937

 2

9 (30)

8 (44.44)

0.3111

 ≥ 3

10 (33.33)

2 (11.11)

0.2598

Basic literacy (reading and writing)

skills (n (%)):

  

0.6228

 Yes

22 (73.33)

12 (66.67)

0.8381

 No

8 (26.67)

6 (33.33)

0.7173

Prenatal antibiotic exposure overall (n (%)):

5 (16.6)

11 (61.1)

0.0049

 1st trimester

0 (0)

1 (5.5)

0.192

 2nd trimester

1 (3.3)

0 (0)

0.4337

 3rd trimester

1 (3.3)

2 (1.1)

0.2812

 Delivery

5 (16.6)

8 (44.4)

0.036

Mode of delivery (n (%)):

  

0.4337

 Vaginal

29 (96.66)

18 (100)

0.9361

 Cesarean section

1 (3.33)

0 (0)

0.4414

No history of smoking (n (%))

30 (100)

18 (100)

 

Gestational age at delivery in days (median (IQR))

279.5 (13.5)

253.5 (16.75)

<0.0001

Birth weight in Kg (median (IQR))

3.07 (0.42)

2.26 (0.53)

<0.0001

Infant length at birth in cm (median (IQR))

48.8 (1.7)

45.6 (3)

<0.0001

Infant head circumference in cm (median (IQR))

33 (1.2)

31 (1.75)

<0.0001

Infant gender (n (%)):

  

0.7091

 Male

15 (50)

10 (55.56)

0.8349

 Female

15 (50)

8 (44.44)

0.8240

  1. Continuous variables were compared using the Mann–Whitney U test. Categorical variables were compared using the Chi-square test where applicable.