Fig. 4: Apilactobacillus kunkeei FM01 modulated serum lipid metabolism in high-fructose diet-fed mice. | npj Science of Food

Fig. 4: Apilactobacillus kunkeei FM01 modulated serum lipid metabolism in high-fructose diet-fed mice.

From: Fructophilic Apilactobacillus kunkeei alleviates high-fructose diet-induced lipid accumulation by modulating gut microbiota and intestinal barrier function in mice

Fig. 4

A Proportions of major lipid subclasses identified in serum samples. B Detected lipid metabolite counts within each subclass. C Principal component analysis (PCA) of serum lipid metabolic profiles across control, high-fructose diet (HFD), and FLAB groups (HFD with A. kunkeei FM01 intervention). D Volcano plot showing differentially regulated lipid metabolites between the HFD and control groups; red denotes upregulated metabolites, green represents downregulated metabolites, and gray indicates non-significant changes. E Heatmap displaying differential lipid metabolites between the FLAB and HFD groups. F Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of differentially regulated lipid metabolites between the FLAB and HFD groups.

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