Fig. 2

Activity of BL neurons during CSs varies depending on behavior. Rats were presented with two CS, one of which predicted reward delivery (CS-R) and the second (CS-N), a neutral outcome. After rats learned to retrieve the liquid reward at the conclusion of the CS-R, the two CSs were presented in random order while recording BL neurons. a Activity of a principal BL cell during multiple presentations of the CS-R. Activity is depicted as a color-coded raster (top) and peri-CS histogram of neuronal discharges (bottom; solid and dashed lines are averages and SEM, respectively). Trials are grouped by behavior as indicated by the colored bar on the left of the rasters (blue, approach of water-port; red, no approach). Rasters and peristimulus histograms in b depict the activity of the same cell as in a, but aligned to onset of water-port approach instead of CS onset. Note higher variations in firing latency when activity is referenced to onset of CS-R than to approach behavior. c Raster and histogram show activity of the same cell when the rat spontaneously initiated approach of the water-port in the absence of CS. White dots in raster indicate time when rats left the water-port. Source: Ref. 48