Table 4 Association of polygenic scores with educational attainment at 16 and school absence at age 14–16a.

From: Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study

 

GCSE points

CI

Absences: % increase

CI

Standardized values of ADHD PGS

−2.70

−4.83, −0.58

−0.24

−2.13, 1.69

Standardized values of depression PGS

0.75

−1.75, 3.25

−0.76

−2.80, 1.32

Standardized values of ASD PGS

−1.78

−3.84, 0.28

−0.41

−2.43, 1.65

Standardized values of migraine PGS

−0.93

−3.04, 1.18

1.38

−0.59, 3.39

Standardized values of asthma PGS

−0.66

−2.80, 1.48

1.18

−0.67, 3.07

Standardized values of BMI PGS

−5.37

−7.78, −2.96

2.72

0.57, 4.91

  1. aN = 6113. Adjusted for gender and PC1–PC20. GCSE points score: range 0–540, mean 332.3, SD 87.4. Coefficients for absences represent proportional change in absenteeism (0% = no change) per SD increase in the polygenic score.
Back to article page