Fig. 8: Survival curves stratified by metabolic states.
From: Computational modeling of cancer cell metabolism along the catabolic-anabolic axes
Survival curves for liver hepatocellular carcinoma (A), melanoma (B), colorectal adenocarcinoma (C), leukemia (D), lung adenocarcinoma (E), and kidney carcinoma (F) datasets. Each dataset was separated into the four metabolic states—‘O’, ‘W’, ‘W/O’, and ‘Q’. Each row in the figure indicates the metabolic state associated with the worst outcome for each cancer dataset. The survival curves were estimated using the Kaplan-Meier method and compared using the log-rank test. Pairwise comparisons of survival distributions stratified by metabolic state are displayed above the survival curve for each pair of metabolic states. Significance levels are indicated as follows: *, P < 0.05; **, P < 0.01; ***, P < 0.001.
