Table 3 Multicompartment network model parameters

From: A Python toolbox for neural circuit parameter inference

Symbol

Value/definition

Description

X

{E, I}

Population names

NX {NE, NI}

{8192, 1024}

Population sizes

\({{\rm{r}}}_{{\rm{X}}\max }({\rm{x}},{\rm{y}})\)

150 μm

Maximum radial position of somas in the XY plane

\({\bar{{\rm{r}}}}_{{\rm{X}}\max }({\rm{z}})\)

0 μm

Mean of the normal distribution that defines the position of somas in the z-axis

\({\rm{\sigma }}\left({{\rm{r}}}_{{\rm{X}}\max }({\rm{z}})\right)\)

75 μm

Standard deviation of the normal distribution that defines the position of somas in the z-axis

\({\mathscr{S}}\)

{soma, apic, basal}

Morphology sections

\({{\rm{L}}}_{{\mathscr{S}}}\)

\(\left\{\begin{array}{l}\left\{30,1000,200\right\}{\rm{\mu }}{\rm{m}}\,{\rm{for}}\,{\rm{X}}={\rm{E}}\\ \left\{30,200,200\right\}{\rm{\mu }}{\rm{m}}\,{\rm{for}}\,{\rm{X}}={\rm{I}}\end{array}\right.\)

Section lengths

\({{\rm{d}}}_{{\mathscr{S}}}\)

\(\left\{\begin{array}{l}\left\{30,3,2\right\}{\rm{\mu }}{\rm{m}}\,{\rm{for}}\,{\rm{X}}={\rm{E}}\\ \left\{15,2,2\right\}{\rm{\mu }}{\rm{m}}{\rm{for}}\,{\rm{X}}\,={\rm{I}}\end{array}\right.\)

Section diameter

\({{\rm{n}}}_{{\rm{seg}}}^{{\mathscr{S}}}\)

\(\left\{\begin{array}{l}\left\{1,21,5\right\}{\rm{for}}\,{\rm{X}}={\rm{E}}\\ \left\{1,5,5\right\}{\rm{for}}\,{\rm{X}}={\rm{I}}\end{array}\right.\)

Number of segments per section

cm

1 μF cm-2

Membrane capacitance

Ra

100 Ω cm

Axial resistivity

\({{\rm{g}}}_{{\rm{L}}}^{{\mathscr{S}}}\)

{0.0000338, 0.0000589, 0.0000589} S cm−2

Passive leak conductance

EL

−90 mV

Passive leak reversal potential

\({\bar{{\rm{g}}}}_{{\rm{N}}{{\rm{a}}}_{{\rm{t}}}}^{{\mathscr{S}}}\)

{2.04, 0.0213, 0.0213} S cm−2

Nat conductance

ENa

50 mV

Na+ reversal potential

\({\bar{{\rm{g}}}}_{{\rm{K}}{{\rm{v}}}_{3.1}}^{{\mathscr{S}}}\)

{0.693, 0.000261, 0.000261} S cm−2

Kv3.1 conductance

EK

−85 mV

K+ reversal potential

\({\bar{{\rm{g}}}}_{{{\rm{I}}}_{{\rm{h}}}}^{{\mathscr{S}}}\)

{0.0002, 0.002, 0.002} S cm−2

Ih current conductance