Fig. 4: Progression-free survival and distribution of ADT failure times in a heterogeneous virtual patient cohort.

a The progression-free survival (PFS) curve showing the fraction of the virtual patient cohort remaining progression-free over time. The accompanying table shows the number of patients for whom therapy had not failed at each time point. b Distribution of ADT failure times across the cohort, highlighting the variability in patient responses. Vertical black lines represent the six patients in the clinical dataset.