Table 1 Effects of different vaccine candidates on BCG-induced rabbit skin lesions
From: The adjuvant effect of manganese on tuberculosis subunit vaccine Bfrb-GrpE
Maximal granuloma size (mm³) (means ± SD) | Initiation of liquefaction (days post- infection) | Onset of ulceration (days post- infection) | Time when liquefied area was maximum (days post- infection) | Lesion volume (mm³) when the liquefied area was maximum (means ± SD) | Bacilli number (CFU/gram) in the liquefied caseum when the liquefied area was maximum | Onset of healing (days post- infection) | Complete healing (days post- infection) | |
|---|---|---|---|---|---|---|---|---|
Control | 691.79 ± 282.56 | 11 | 16 | 17 | 2199.59 ± 969 | 5.38×106 | 24 | 29 |
BCG | 526.02 ± 168.03 | 8 | 10 | 15 | 2202.87 ± 231 | 3.49×106 | 18 | 28 |
BG-DP | 312.88 ± 105.03 | 7 | 9 | 13 | 2565.5 ± 920 | 2.40×106 | 24 | 29 |
BG-Mn(J) | 1174.62 ± 599.05* | 8 | 10 | 13 | 7252.61 ± 2946* | 1.33×106 | 18 | 24 |
