Fig. 3: LukAB RARPR-33 toxoid compared to LukAB CC8Δ10C toxoid. | npj Vaccines

Fig. 3: LukAB RARPR-33 toxoid compared to LukAB CC8Δ10C toxoid.

From: A SpA+LukAB vaccine targeting Staphylococcus aureus evasion factors restricts infection in two minipig infection models

Fig. 3

A LukAB shows highest toxicity at the lowest concentrations among leukocidins produced by S. aureus.B Lower in vitro cytotoxicity of LukAB RARPR-33 than prototype LukAB CC8Δ10C. CC clonal complex, Hlg gamma-hemolysin locus, LukAB leukocidin AB, LukED leukocidin ED, PVL Panton-Valentine leukocidin, PMN polymorphonuclear cells, WT wild-type.

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