Fig. 2: The preclinical design for evaluating the EDIII-Qβ vaccine. | npj Vaccines

Fig. 2: The preclinical design for evaluating the EDIII-Qβ vaccine.

From: A VLPs based vaccine protects against Zika virus infection and prevents cerebral and testicular damage

Fig. 2

The animal experiments were conducted in six independent studies: three to evaluate the humoral and cellular immune responses and neutralizing antibodies in C57BL/6 mice, and three to perform viral challenge experiments in male and female G129 mice. Samples were analyzed using ELISA, flow cytometry, CPE-VNT, qPCR, and histological studies to assess immune response, viral neutralization, and tissue integrity. Created with BioRender.

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