Fig. 4: Determination of immune responses. | npj Vaccines

Fig. 4: Determination of immune responses.

From: Development of a broad-spectrum subunit vaccine against H9N2 avian influenza using HA stem domain scaffold and snoopligase system

Fig. 4

a Specific antibody titer against the SN virus. b Specific antibody titer against the YZ4 virus. c Specific antibody titer against the SN virus at 42 d.p.i. d Specific antibody titer against the YZ4 virus at 42 d.p.i. e–h Cytokine level measurement after primary immunization. i–l Cytokine level measurement after booster immunization. m, n Detection of lymphocyte proliferation. o, p ELISpot detection after the YZ4 and SN viruses stimulation. Statistical analysis was performed using the one-way ANOVA. Error bar, mean ± SD.

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