Table 1 Virus shedding rate and protection index in vaccinated chickens after challenge

From: Development of a broad-spectrum subunit vaccine against H9N2 avian influenza using HA stem domain scaffold and snoopligase system

Immunization group

Challenge viruses

Days post challenge

3 d.p.c

 

5 d.p.c

  

7 d.p.c

 

Ta

Cb

T

C

T

C

Virus shedding ratec

Protection indexd

Virus shedding rate

Protection index

Virus shedding rate

Protection index

Virus shedding rate

Protection index

Virus shedding rate

Protection index

Virus shedding rate

Protection index

PBS

SN

8/8c

-e

8/8

-

8/8

-

4/8

-

8/8

-

0/8

-

PBS

YZ4

8/8

-

8/8

-

8/8

-

2/8

-

4/8

-

0/8

-

HA6

SN

8/8

/f

6/8

25.00%

7/8

12.50%

1/8

75.00%

3/8

62.50%

0/8

-

HA6

YZ4

5/8

37.50%

4/8

50.00%

3/8

62.50%

0/8

100.00%

0/8

100.00%

0/8

-

fPE

SN

8/8

/

3/8

62.50%

8/8

/

2/8

50.00%

5/8

37.50%

0/8

-

fPE

YZ4

8/8

/

4/8

50.00%

8/8

/

1/8

50.00%

4/8

/

0/8

-

fPE-HA6

SN

6/8

25.00%

4/8

50.00%

5/8

37.50%

0/8

100.00%

1/8

87.50%

0/8

-

fPE-HA6

YZ4

6/8

25.00%

4/8

50.00%

2/8

75.00%

0/8

100.00%

0/8

100.00%

0/8

-

TX

SN

7/8

12.50%

4/8

50.00%

4/8

50.00%

1/8

75.00%

0/8

100.00%

0/8

-

TX

YZ4

5/8

37.50%

4/8

50.00%

1/8

87.50%

0/8

100.00%

0/8

100.00%

0/8

-

  1. aThroat swab.
  2. bCloacal swab.
  3. cShedding rate: shedding number/total number.
  4. dProtection index: (Number of shedding in PBS group − number of shedding in immunized group)/number of shedding count in PBS group.
  5. eUncalculated.
  6. fUnprotected.
Back to article page