Fig. 4: mRNA LNP vaccines induce strong and durable cellular immunity in Balb/c mice. | npj Vaccines

Fig. 4: mRNA LNP vaccines induce strong and durable cellular immunity in Balb/c mice.

From: A multivalent mRNA-LNP cocktail vaccine confers superior efficacy against Staphylococcus aureus infection in murine models

Fig. 4

CD8+ T cells and CD4+ T cells in splenic lymphocytes were assayed for IFN-γ+ (A, B), IL-2+ (C, D), IL-4+ (E, F), and IL-17A+ (G, H) expression by flow cytometry after restimulation with corresponding proteins. Data are represented as mean ± SD and analyzed by one-way ANOVA with Tukey’s multiple comparisons test. n = 5. ns represents no significant. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), and p < 0.0001 (****).

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