Extended Data Fig. 8: The potential mechanism of the cell migration speed trends on collagen of gradient strain48. | Nature Biomedical Engineering

Extended Data Fig. 8: The potential mechanism of the cell migration speed trends on collagen of gradient strain48.

From: Tension-induced directional migration of hepatic stellate cells potentially coordinates liver fibrosis progression

Extended Data Fig. 8

a, The four steps in the classic ‘motor-clutch’ model of cell migration. We focus on the release stage to explain the cell migration trends. b, The potential mechanism to explain why quiescent HSCs have the ‘increase and decrease’ trend of migration speed on collagen of gradient strain. c, The potential mechanism to explain why the migration speed of activated HSCs don’t change evidently on collagen of gradient strain.

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