Extended Data Fig. 5: Comparative analysis of HLBO with published human organoid datasets. | Nature Biomedical Engineering

Extended Data Fig. 5: Comparative analysis of HLBO with published human organoid datasets.

From: Self-organization of sinusoidal vessels in pluripotent stem cell-derived human liver bud organoids

Extended Data Fig. 5

a) UMAPs for human pluripotent stem cell-derived liver organoid cell atlas colored by cell type and organoid source. b) UMAPs display the maximum spearman correlation of (left) adult liver and (right) fetal liver dataset. The right UMAP highlights HLBO+iLSEP cells. c-f) Ridge plots displaying spearman correlations for each organoid dataset against c) adult or fetal hepatocytes, d) adult or fetal cholangiocytes, e) both adult and fetal stellate cells, and f) adult or fetal endothelial cells. Organoid groups that did not contain enough cells to show data distribution are not plotted.

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