Extended Data Fig. 10: Jawbone regeneration by transplanted jawbone-like organoids and bone graft.
From: Jawbone-like organoids generated from human pluripotent stem cells
a, Schematic representation of jawbone-like organoid (d38) transplantation into mandibular bone defects in NSG mice. b, A micro-CT scanning image of bone defect before transplantation. c–e, Individual micro-CT scanning images of jawbones with no graft (c), with jawbone-like organoid transplantation (d) and with bone graft (e). (n = 8). f, HE and Azan staining in serial sections of bone-grafted tissues at 4 weeks post-transplantation (decalcified specimens). (n = 6). Scale bars, 200 μm. Representative data are shown.
