Extended Data Fig. 2: Images indicating fluid movement across the self-contained ASTRA chip. | Nature Biomedical Engineering

Extended Data Fig. 2: Images indicating fluid movement across the self-contained ASTRA chip.

From: Self-powered rapid antigen-specific T-cell response assay for Mycobacterium tuberculosis infections

Extended Data Fig. 2

Cell samples (pink) and the two ASTRA antibody reagents (green) and nuclear stain to migrate across the chip upon loading, allowing the cells to be captured on the antibody-conjugated cell loading channel, and segregating the antibodies from these samples until after the peptide-mediated stimulation reaction is complete. Sliding the cases all material to migrate “upwards” along the length of the chip at a constant rate so that the staining reagents interact with the captured cells for a set interval determined by the chip flow rate before being washed away by PBS loaded in three of the downstream channels of the chip.

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