Extended Data Fig. 9: Proteomics study of protein coronas formed on LNP-168-Luc. | Nature Biomedical Engineering

Extended Data Fig. 9: Proteomics study of protein coronas formed on LNP-168-Luc.

From: In vivo genome editing of human haematopoietic stem cells for treatment of blood disorders using mRNA delivery

Extended Data Fig. 9

a. Schematic showing the use of mass spectrometry in the analysis of LNPs mRNA with proteins in the plasma interactions. b. Heat map of the average abundance of proteins with distinct biological functions in the protein coronas of LNP-168-Luc. c. Quantification of percentage of total proteins of the top three protein components in the protein corona of the LNP-168-Luc is shown. Data are representative of three biologically independent replicates. Data are shown as mean ± SD.

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