Extended Data Fig. 1: IR-induced p21 expression is coupled with hair cycle progression.
From: Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma
a, Appearance of young (2 months old) and of old (23 months old) C57BL/6N mice with some gray hairs. White arrowheads indicate gray hairs. b, Graph showing the percentage of gray hairs per 100 hairs (Young; n=3, Old; n=10, biological independent experiments). Data are presented as means ± SEM. Mann-Whitney’s U test. c, Immunohistological analysis of the bulge of Dct-H2B-GFP KI mice at the indicated time points with or without IR. Arrowheads indicate p21+ McSCs (GFP+ cells). Scale Bar = 50 μm. Dp; Hair depilation.
