Extended Data Fig. 4: Proposed dehydrative cyclization model of Abx(−)F. | Nature Chemistry

Extended Data Fig. 4: Proposed dehydrative cyclization model of Abx(−)F.

From: An enzymatic dual-oxa Diels–Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (–)-anthrabenzoxocinone

Extended Data Fig. 4

a, Proposed reaction diagram of dehydrative cyclization. b, MS spectra of 18O labeled or unlabeled substrate and products in Abx(−)E and Abx(−)F assay. (i) MS spectra of 18O-1 in boiled Abx(−)E and boiled Abx(−)F assay; (ii) MS spectra of 1 in boiled Abx(−)E and boiled Abx(−)F assay; (iii) MS spectra of products 18O-2, 18O-5, 18O-(+)-ABX and 18O-(−)-ABX in Abx(−)E and boiled Abx(−)F assay; (iv) MS spectra of products 2, (+)-ABX and (−)-ABX in Abx(−)E and boiled Abx(−)F assay; (v) MS spectra of product 18O-(−)-ABX in Abx(−)E and Abx(−)F assay; (vi) MS spectra of product (−)-ABX in Abx(−)E and Abx(−)F assay.

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