Extended Data Fig. 4: Mechanistic investigations of SnPolE.
From: A two-metalloenzyme cascade constructs the azetidine-containing pharmacophore
a, The potential energy surface (in kcal mol−1) of SnPolE-catalyzed desaturation reaction obtained from QM/MM calculations. b, The structures of key intermediates involved in the SnPolE-catalyzed desaturation reaction.
