Extended Data Fig. 1: Experimental mechanistic studies.
From: Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres
a, Radical clock experiment. b, Tracking the enantiopurity of the secondary α-chloroamides. c, Stereodivergent synthesis of 3. Standard condition: 1a (1.0 equiv.), 2 (1.5 equiv.), CoI2 (5 mol%), L4 (6 mol%), In (2.0 equiv.), EtOH (1.0 equiv.) in MeCN/THF (v/v = 1/1, 0.2 M) under 35 °C for 48 h. Isolated yields were reported, the e.e. was determined by chiral HPLC analysis and d.r. was determined by crude NMR.
