Extended Data Fig. 7: Metabolomic measurement of butyrate in blood shows weak but significant correlation with MCMM-predicted butyrate production.
MCMM predicted values of butyrate production fluxes from the gut microbiome show weak, but significant association with blood metabolomic measures of circulating butyrate in the Arivale cohort (Pearson’s Correlation r = 0.053, p = .003). Each point represents one individual. Pearson’s correlation r value and associated two-tailed p-value were calculated across all points. The dashed black line denotes a linear regression line and the gray area denotes the 95% confidence interval of the regression line.
