Extended Data Fig. 7: Multi-cytokine antigen-specific T cell responses in vaccinees. | Nature Microbiology

Extended Data Fig. 7: Multi-cytokine antigen-specific T cell responses in vaccinees.

From: Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans

Extended Data Fig. 7

Correlation analysis of concentration of IFN-γ in C peptide-stimulated whole blood and the corresponding concentrations of IL-2 (a), granzyme-B (b), IL-10 (c) and TNF-α (d) (n = 16). Two-tailed Spearman’s correlation. Dotted lines denote the 95% confidence interval. e-g, Concentration of secreted cytokines in C (e), NS3 (f) and NS5 (g) stimulated whole-blood of vaccinees with (n = 8, blue bars; mean) and without (n = 8, red bars; mean) detectable RNAemia post-challenge. Circles represent individual vaccinees. P values calculated with two-tailed unpaired Mann-Whitney U test. ns, not significant.

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